Orsini Marco, Henrique de Gobbi Porto Fábio, Fernandes do Nascimento Jacqueline
Master's Program in Neurology - University of Vassouras and School of Medicine, University Iguaçu, RJ, Brazil.
Laboratory of Psychiatric Neuroimaging (LIM-21) and Old Age Research Group (PROTER), Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Psychiatry Res Commun. 2021 Dec;1(2):100004. doi: 10.1016/j.psycom.2021.100004. Epub 2021 Oct 28.
Covid-19-related encephalitis is a heterogeneous syndrome characterized by a combination of clinical, laboratory, and imaging features related to inflammation of the brain, where the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is presumably the causative agent. We reported a case of Covid-19-related encephalitis presenting with neuropsychiatric symptoms, including intense agitation. Reverse-transcriptase polymerase-chain-reaction in cerebrospinal fluid was positive for SARS-CoV-2. Our case expands the literature about neurologic manifestations of Covid-19 and emphasizes the possibility of prominent behavioral symptoms as the initial manifestation.
新型冠状病毒肺炎（Covid-19）相关脑炎是一种异质性综合征，其特征为与脑部炎症相关的临床、实验室及影像学特征的组合，推测严重急性呼吸综合征冠状病毒2（SARS-CoV-2）为致病原。我们报告了1例表现为神经精神症状（包括强烈激越）的Covid-19相关脑炎病例。脑脊液逆转录聚合酶链反应检测显示SARS-CoV-2呈阳性。我们的病例扩展了关于Covid-19神经系统表现的文献，并强调了突出行为症状作为首发表现的可能性。
