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新型冠状病毒肺炎相关脑炎的神经精神表现:病例报告

Neuropsychiatric presentation of Covid-19-related encephalitis: Case report.

作者信息

Orsini Marco, Henrique de Gobbi Porto Fábio, Fernandes do Nascimento Jacqueline

机构信息

Master's Program in Neurology - University of Vassouras and School of Medicine, University Iguaçu, RJ, Brazil.

Laboratory of Psychiatric Neuroimaging (LIM-21) and Old Age Research Group (PROTER), Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.

出版信息

Psychiatry Res Commun. 2021 Dec;1(2):100004. doi: 10.1016/j.psycom.2021.100004. Epub 2021 Oct 28.

Abstract

Covid-19-related encephalitis is a heterogeneous syndrome characterized by a combination of clinical, laboratory, and imaging features related to inflammation of the brain, where the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is presumably the causative agent. We reported a case of Covid-19-related encephalitis presenting with neuropsychiatric symptoms, including intense agitation. Reverse-transcriptase polymerase-chain-reaction in cerebrospinal fluid was positive for SARS-CoV-2. Our case expands the literature about neurologic manifestations of Covid-19 and emphasizes the possibility of prominent behavioral symptoms as the initial manifestation.

摘要

新型冠状病毒肺炎(Covid-19)相关脑炎是一种异质性综合征,其特征为与脑部炎症相关的临床、实验室及影像学特征的组合,推测严重急性呼吸综合征冠状病毒2(SARS-CoV-2)为致病原。我们报告了1例表现为神经精神症状(包括强烈激越)的Covid-19相关脑炎病例。脑脊液逆转录聚合酶链反应检测显示SARS-CoV-2呈阳性。我们的病例扩展了关于Covid-19神经系统表现的文献,并强调了突出行为症状作为首发表现的可能性。

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本文引用的文献

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How COVID-19 Affects the Brain.新冠病毒如何影响大脑。
JAMA Psychiatry. 2021 Jun 1;78(6):682-683. doi: 10.1001/jamapsychiatry.2021.0500.
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Neurologic complications of COVID-19.COVID-19 的神经系统并发症。
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