自闭症谱系障碍和脆性 X 综合征男性青少年和成年患者焦虑症的患病率及其预测因素。
Prevalence and Predictors of Anxiety Disorders in Adolescent and Adult Males with Autism Spectrum Disorder and Fragile X Syndrome.
机构信息
Department of Psychology, University of South Carolina, 1512 Pendleton Street, Barnwell College, Suite 220, Columbia, SC, 29208, USA.
Communication Sciences and Disorders, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
出版信息
J Autism Dev Disord. 2019 Mar;49(3):1131-1141. doi: 10.1007/s10803-018-3804-6.
Abstract
Anxiety disorders affect ~ 15-20% of youths without neurodevelopmental disorders, with persons having autism spectrum disorder (ASD) and fragile X syndrome (FXS) at elevated risk for anxiety disorders. Few studies have compared rates and predictors of anxiety disorders in adolescents with FXS or ASD. This study directly compares rates, predictors, and medication of anxiety disorders between age-matched, male adolescents with FXS (n = 31) or ASD (n = 20). Results indicate that 51.6% of FXS and 50.0% of ASD adolescents met criteria for an anxiety disorder. Cognitive scores and ASD severity did not predict anxiety. Of those with anxiety, ~ 40% of the FXS and 20% of the ASD participants were prescribed medications for anxiety.
摘要
焦虑障碍影响约 15-20%无神经发育障碍的青少年，自闭症谱系障碍（ASD）和脆性 X 综合征（FXS）患者患焦虑障碍的风险增加。很少有研究比较 FXS 或 ASD 青少年焦虑障碍的发生率和预测因素。本研究直接比较了年龄匹配的男性 FXS（n=31）或 ASD（n=20）青少年的焦虑障碍发生率、预测因素和药物治疗。结果表明，51.6%的 FXS 青少年和 50.0%的 ASD 青少年符合焦虑障碍标准。认知评分和 ASD 严重程度不能预测焦虑。在患有焦虑症的患者中，约 40%的 FXS 和 20%的 ASD 参与者被开了焦虑症药物。
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