Suppr超能文献

新冠 mRNA 疫苗接种后发生心肌炎并发心源性休克:摩洛哥首例病例报告及简要回顾

Cardiogenic shock revealing myocarditis after mRNA vaccination against covid-19: Case report and brief review for the first case in Morocco.

作者信息

Mimouni Hamza, Bahouh Choukri, Amaqdouf Saida, Laaribi Ilyass, Baddi Mohammed, Berichi Samya, Bkiyar Houssam, Ismaili Nabila, El Ouafi Noha, Housni Brahim

机构信息

Faculty of Medicine and Pharmacy, Mohammed I University, Oujda, Morocco.

Department of Anesthesiology and Intensive Care Unit, Mohammed VI University Hospital Mohammed I University, Oujda, Morocco.

出版信息

Ann Med Surg (Lond). 2022 Feb;74:103210. doi: 10.1016/j.amsu.2021.103210. Epub 2021 Dec 30.

Abstract

INTRODUCTION

and importance: After its unexpected effectiveness in the clinical trials, the anti-COVID-19 vaccine type mRNA was launched on December 11, 2020, but a few months later, several reports of post-mRNA vaccination myocarditis were published, but without any proven causal link.

CASE PRESENTATION

We report the case of a 14-year-old teenager admitted to the emergency department for a cardiogenic shock, the patient mentioned that he had an anti-COVID 19 vaccination 10 days before his admission. First, the vasoactive drugs had stabilized the patient; the troponins came back highly favorable but later confirmed myocarditis by magnetic resonance imaging. In this sense an etiological analysis was made and it came back without any particularities, leaving us relating the myocarditis to the vaccination.

CLINICAL DISCUSSION

Post-vaccination myocarditis is a rare event, with very few reports in the literature. After the introduction of COVID vaccination, several reports were published, mostly after the mRNA vaccine. Until now, no causal link has been proven, so we need to have more reports in this sense to have a better knowledge of this phenomenon.

CONCLUSION

Until we obtain a more precise explanation of the mechanism of myocarditis after vaccination with the anti-COVID-19 vaccine, all symptoms suggesting myocarditis should be systematically monitored during the first 7 days after vaccination.

摘要

引言

及其重要性:在临床试验中意外取得成效后,新冠mRNA疫苗于2020年12月11日推出,但几个月后,陆续发表了几篇关于mRNA疫苗接种后心肌炎的报告,但尚未证实有任何因果关系。

病例报告

我们报告一例14岁青少年因心源性休克入住急诊科的病例,该患者称在入院前10天接种了新冠疫苗。首先,血管活性药物使患者病情稳定;肌钙蛋白结果起初显示情况良好,但后来通过磁共振成像确诊为心肌炎。就此进行了病因分析,未发现任何特殊情况,我们认为心肌炎与疫苗接种有关。

临床讨论

接种疫苗后发生的心肌炎是一种罕见事件,文献报道极少。新冠疫苗接种后,陆续发表了几篇报告,大多是关于mRNA疫苗接种后的情况。到目前为止,尚未证实有因果关系,因此我们需要更多这方面的报告,以便更好地了解这一现象。

结论

在我们获得关于接种新冠疫苗后心肌炎机制的更精确解释之前,接种疫苗后的前7天应系统监测所有提示心肌炎的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8c3/8760492/b57bcfef3168/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验