Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran.
Chronic Kidney Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Adv Exp Med Biol. 2021;1328:531-544. doi: 10.1007/978-3-030-73234-9_38.
The use of herb-based therapies is increasing over the past decades. These agents have been reported to provide many beneficial effects in many experimental and clinical studies. Curcumin is one of these agents which has potent pharmacological effects enabling it for the prevent and treatment of many diseases and pathologies such as renal disorders, hyperglycemia, oxidative stress, hypertension, and dyslipidemia. However, the exact molecular mechanisms mediating these renoprotective effects of curcumin are not well established. So, in the current study, we surveyed for possible renoprotective roles of curcumin and concluded how curcumin protects against renal injuries.
在过去几十年中，基于草药的治疗方法的使用正在增加。这些药物已在许多实验和临床研究中被报道具有许多有益的作用。姜黄素就是其中一种药物，它具有强大的药理作用，可用于预防和治疗许多疾病和病理，如肾脏疾病、高血糖、氧化应激、高血压和血脂异常。然而，介导姜黄素这些肾脏保护作用的确切分子机制尚未得到很好的确定。因此，在本研究中，我们调查了姜黄素的可能的肾脏保护作用，并得出了姜黄素如何预防肾脏损伤的结论。
