Department of Neurosurgery, University of Illinois, Chicago.
Stroke. 2022 Feb;53(2):624-633. doi: 10.1161/STROKEAHA.121.037147. Epub 2022 Jan 5.
Sex differences in cerebral aneurysm occurrence and characteristics have been well described. Although sex differences in outcomes following ischemic stroke have been identified, the effect of sex on outcomes following hemorrhagic stroke, and in particular, aneurysm treatment has been less studied. We describe the current state of knowledge regarding the impact of sex on treatment and outcomes of cerebral aneurysms. Although prior studies suggest that aneurysm prevalence and progression may be related to sex, we did not find clear evidence that outcomes following subarachnoid hemorrhage vary based on sex. Last, we identify areas for future research that could enhance understanding of the role sex plays in this context.
性别与脑动脉瘤的发生和特征存在明显相关性,这一点已得到充分证实。虽然人们已经认识到性别与缺血性脑卒中结局之间存在差异,但对于性别对出血性脑卒中结局的影响,特别是对动脉瘤治疗的影响,研究相对较少。我们描述了目前关于性别的影响在脑动脉瘤治疗和结局方面的知识状况。虽然先前的研究表明,动脉瘤的患病率和进展可能与性别有关,但我们没有发现明确的证据表明蛛网膜下腔出血后的结局因性别而异。最后,我们确定了未来研究的领域,这可能有助于增强对性别的作用的理解。