Roussel T J, Culbertson W W, Jaffe N S
Arch Ophthalmol. 1987 Sep;105(9):1199-201. doi: 10.1001/archopht.1987.01060090057026.
We present two cases of Propionibacterium acnes endophthalmitis that confirm the association of this organism with a delayed onset and chronic and indolent intraocular inflammation following extracapsular cataract extraction with posterior chamber intraocular lens implantation. The clinical, microbiologic, and histopathologic features of these cases suggest that the organism can be sequestered in the capsular bag, which may make this entity difficult to diagnose. We conclude that complete capsulectomy may be required if inflammation persists after conventional treatment for endophthalmitis, which may include pars plana vitrectomy, partial capsulectomy, and antibiotic therapy. Sterile postoperative uveitis is a diagnosis of exclusion. We stress the importance of appropriate microbiologic investigation in all cases of postsurgical inflammation, even if the onset is delayed until several months after surgery.
我们报告了两例痤疮丙酸杆菌性眼内炎病例，证实了该病原体与白内障囊外摘除联合后房型人工晶状体植入术后延迟发作以及慢性、惰性眼内炎症之间的关联。这些病例的临床、微生物学和组织病理学特征表明，该病原体可能隐匿于晶状体囊袋内，这可能导致该疾病难以诊断。我们得出结论，如果在眼内炎的常规治疗（可能包括玻璃体切割术、部分晶状体囊切除术和抗生素治疗）后炎症仍持续存在，则可能需要进行彻底的晶状体囊切除术。无菌性术后葡萄膜炎是一种排除性诊断。我们强调，在所有术后炎症病例中，即使炎症发作延迟至术后数月，进行适当的微生物学检查也非常重要。
