在一项基于人群的研究中，考察鸦片使用、吸烟和饮酒与肝酶水平之间的关联：法萨波斯队列研究数据。
Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data.
机构信息
Department of Medical Surgical Nursing, Fasa University of Medical Sciences, Fasa, Iran.
Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
出版信息
BMC Res Notes. 2022 Jan 5;15(1):2. doi: 10.1186/s13104-021-05891-3.
OBJECTIVES
Opium use, cigarette smoking, and alcohol consumption are serious health problems in many countries including Iran. The present study aimed to examine the association between the opium use, cigarette smoking and alcohol consumption with liver enzyme levels in Southern Iran. This analytical cross-sectional study was conducted in 2020. The entire population of the Fasa Persian cohort study in the southern region of Iran was selected as the sample. Accordingly, 10,145 people participated in the study.
RESULTS
Results indicated that there was a significant relationship between cigarette smoking and alcohol consumption with liver enzymes (AST, ALT, and ALP). There was also a significant relationship between inhaled opium and liver enzymes, but oral opium revealed no significant relationship with the activity of liver enzymes. Accordingly, policymakers of the health care system are recommended to hold educational programs to improve the health literacy level of the society and take effective preventative strategies in reducing the use of these substances.
目的
在包括伊朗在内的许多国家，鸦片使用、吸烟和饮酒都是严重的健康问题。本研究旨在探讨伊朗南部地区鸦片使用、吸烟和饮酒与肝酶水平之间的关系。这项分析性横断面研究于 2020 年进行。伊朗南部法斯阿波斯 cohort 研究的全部人群被选为样本。因此，共有 10145 人参加了这项研究。
结果
结果表明，吸烟和饮酒与肝酶（AST、ALT 和 ALP）之间存在显著关系。吸入式鸦片与肝酶之间也存在显著关系，而口服鸦片与肝酶活性之间没有显著关系。因此，建议医疗保健系统的政策制定者举办教育计划，提高社会的健康素养水平，并采取有效预防策略来减少这些物质的使用。
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