伊朗东南部拉夫桑詹地区口腔念珠菌病与香烟、烟草、酒精和鸦片消费的关系。

Oral candidiasis and cigarette, tobacco, alcohol, and opium consumption in Rafsanjan, a region in the southeast of Iran.

机构信息

Department of Epidemiology, School of Public Health, Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Department of Oral Medicine, Dental School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

出版信息

BMC Oral Health. 2023 May 5;23(1):262. doi: 10.1186/s12903-023-02969-1.

DOI:10.1186/s12903-023-02969-1

PMID:37147684

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10161623/

Abstract

BACKGROUND

We investigated the association between oral candidiasis prevalence and cigarette, tobacco, alcohol, and opium consumption in Rafsanjan, a region in the southeast of Iran.

METHODS

This cross-sectional study was conducted using the data of Oral Health Branch of Rafsanjan Cohort Study (OHBRCS) as a part of the Rafsanjan Cohort Study (RCS). RCS included in Prospective Epidemiological Research Studies in IrAN (PERSIAN) was begun in 2015 in the Rafsanjan. A full-mouth examination was done by trained dental specialists. Oral candidiasis was diagnosed based on clinical examination. Information about cigarette, tobacco, and opium smoking and alcohol consumption were collected based on data from self-reported questionaries. Univariate and multivariate dichotomous logistics regression were used to assess the association between oral candidiasis and cigarette, tobacco, alcohol, and opium consumption.

RESULTS

Among 8682 participants with mean age of 49.94 years, the prevalence of oral candidiasis was 7.94%. There was a direct association between cigarette smoking in current and former cigarette smokers with an increased odds of oral candidiasis (OR: 3.26, 95% CI: 2.46-4.33 and OR: 1.63, 95% CI: 1.18-2.25 respectively) in fully adjusted models. There was a dose-response relationship between the odds of oral candidiasis and dose (OR: 3.31, 95% CI: 2.38-4.60), duration (OR: 2.48, 95% CI: 2.04-3.95) and number (OR: 3.01, 95% CI: 2.02-4.50) of cigarette smoking in the 4th quartile compared to reference group.

CONCLUSIONS

A dose-response relationship was shown between cigarette smoking and increased odds of oral candidiasis.

摘要

背景

我们研究了伊朗东南部拉夫桑詹地区口腔念珠菌病患病率与吸烟、烟草、酒精和鸦片消费之间的关系。

方法

本横断面研究使用拉夫桑詹队列研究（RCS）口腔健康分部（OHBRCS）的数据进行，该研究是伊朗前瞻性流行病学研究（PERSIAN）的一部分。RCS 于 2015 年在拉夫桑詹开始。由经过培训的牙科专家进行全口检查。根据临床检查诊断口腔念珠菌病。根据自我报告问卷中的数据收集关于吸烟、烟草和鸦片吸烟和饮酒的信息。采用单变量和多变量二项逻辑回归评估口腔念珠菌病与吸烟、烟草、酒精和鸦片消费之间的关系。

结果

在 8682 名平均年龄为 49.94 岁的参与者中，口腔念珠菌病的患病率为 7.94%。在完全调整的模型中，当前和以前的吸烟者吸烟与口腔念珠菌病的患病风险增加呈直接相关（OR：3.26，95%CI：2.46-4.33 和 OR：1.63，95%CI：1.18-2.25）。在第四四分位组中，吸烟量（OR：3.31，95%CI：2.38-4.60）、吸烟时间（OR：2.48，95%CI：2.04-3.95）和吸烟次数（OR：3.01，95%CI：2.02-4.50）与口腔念珠菌病的患病风险之间存在剂量反应关系。