Division of Cardiovascular Medicine, University of Missouri, Columbia, MO 65212, United States; Harry S. Truman Memorial Veterans Hospital, Columbia, MO, United States.
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO 65212, United States; Harry S. Truman Memorial Veterans Hospital, Columbia, MO, United States.
Explore (NY). 2022 Nov-Dec;18(6):714-718. doi: 10.1016/j.explore.2021.12.003. Epub 2021 Dec 23.
Morbid obesity (BMI > 35 kg/m2 with comorbid conditions) is present in 25 - 35% of acute decompensated heart failure (AHF) patients. Prevalence of HF increases with duration of morbid obesity from 30% at 15 years to over 90% at 30 years. There is a need to develop pragmatic therapies that address the unique physical and mental challenges faced by obese AHF patients. Siddha is 5,000 year old Tamil Medicine using yoga and mind-body methods towards higher consciousness. Hunger gratitude Experience (HUGE) is intuitive Siddha fasting method which may improve in-hospital AHF outcomes independent of weight reduction.
We present 5 cases of morbidly obese patients with cardiorenal syndrome (CRS) that began intermittent fasting either during their AHF hospitalization or in the outpatient setting for refractory symptoms despite hospitalization. Initiation of fasting correlated with reduction of respiratory distress and edema as well as improvements in psychological wellbeing and functional capacity.
Siddha fasting mediates hemodynamic and anti-inflammatory effects through natural ketosis and psychological benefits through empowerment in AHF. Potential role of fasting in reducing myocardial workload, coronary steal, angina, volume overload, and CRS needs further study in cardiac patients.
病态肥胖(BMI>35kg/m2 合并并存疾病)存在于 25%-35%的急性失代偿性心力衰竭(AHF)患者中。HF 的患病率随着病态肥胖持续时间的增加而增加,从 15 年的 30%增加到 30 年的 90%以上。需要开发实用的治疗方法来解决肥胖 AHF 患者面临的独特的身体和心理挑战。Siddha 是一种有 5000 年历史的泰米尔医学,它使用瑜伽和身心方法来提高意识。饥饿感恩体验(HUGE)是一种直观的 Siddha 禁食方法,它可能会改善住院 AHF 患者的预后,而与体重减轻无关。
我们介绍了 5 例患有心肾综合征(CRS)的病态肥胖患者,他们在 AHF 住院期间或在因难治性症状而住院的情况下开始间歇性禁食。禁食的开始与呼吸困难和水肿的减轻以及心理幸福感和功能能力的改善相关。
Siddha 禁食通过自然酮症和通过授权在 AHF 中获得心理益处来介导血液动力学和抗炎作用。禁食在降低心肌工作量、冠状窃血、心绞痛、容量超负荷和 CRS 中的潜在作用需要在心脏病患者中进一步研究。