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首例 50 天连续禁食治疗有症状多支冠状动脉疾病和心力衰竭:通过自然酮症实现心脏保护

First Report Of 50-Day Continuous Fasting in Symptomatic Multivessel Coronary Artery Disease and Heart Failure: Cardioprotection Through Natural Ketosis.

机构信息

Division of Cardiovascular Medicine, University of Missouri, Columbia, Missouri.

Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

出版信息

Mo Med. 2022 May-Jun;119(3):250-254.

PMID:36035583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9324723/
Abstract

A 64-year-old man with angina and dyspnea due to severe two vessel coronary artery disease (CAD) was recommended for revascularization. The patient had recently learned Siddha fasting and self-inquiry meditative methods at Heartful Living, our eight-week physicianled cardiac wellness group clinic. He declined coronary artery bypass surgery and instead self-initiated a 50-day water-only fast and then switched to a vegan diet. During the fast, the patient experienced severe dehydration and electrolyte abnormalities, requiring IV fluids and electrolyte replacement. However, his hemodynamics remained stable and he had no angina, likely due to natural ketosis mediated cardioprotection. This is the first report of such a prolonged fast targeting cardiac resilience and clinical benefits in severe CAD.

摘要

一位 64 岁男性因严重两血管冠状动脉疾病(CAD)引起的心绞痛和呼吸困难,被建议进行血运重建。该患者最近在我们的八周医师主导的心脏健康小组诊所 Heartful Living 学习了 Siddha 禁食和自我探究冥想方法。他拒绝了冠状动脉旁路手术,而是自行开始了 50 天的仅饮水禁食,然后转为素食饮食。在禁食期间,患者经历了严重的脱水和电解质异常,需要静脉输液和电解质替代。然而,他的血液动力学保持稳定,没有心绞痛,可能是由于自然酮体介导的心脏保护作用。这是首例关于针对严重 CAD 的心脏弹性和临床获益的如此长时间禁食的报告。

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本文引用的文献

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Explore (NY). 2022 Nov-Dec;18(6):714-718. doi: 10.1016/j.explore.2021.12.003. Epub 2021 Dec 23.
2
Siddha fasting in morbidly obese heart failure patients achieves significant weight loss and reduces hospitalization.西达禁食法应用于病态肥胖的心力衰竭患者可实现显著减重并减少住院次数。
Explore (NY). 2021 Nov 25. doi: 10.1016/j.explore.2021.11.006.
3
Higher Consciousness Through Self-Inquiry Can Improve Cardio Metabolic Outcomes, Mental Health, and Resilience.通过自我探究实现更高意识可改善心血管代谢状况、心理健康和恢复力。
Mo Med. 2021 Mar-Apr;118(2):97-102.
4
Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease: JACC State-of-the-Art Review.酮体对心血管疾病患者的治疗潜力:美国心脏病学会的最新综述。
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