索马里摩加迪沙一家三级转诊医院甲状腺疾病的谱和患病率：976例回顾性研究
Spectrum and Prevalence of Thyroid Diseases at a Tertiary Referral Hospital in Mogadishu, Somalia: A Retrospective Study of 976 Cases.
作者信息
Hassan-Kadle Mohamed A, Adani Abdulkamil Abdullahi, Eker Hasan Huseyin, Keles Esra, Muse Osman Marian, Mahdi Ahmed Hussein, Görçin Karaketir Şeyma
机构信息
SomGastro Clinic, Center for Digestive and Liver Disease, College of Medicine & Health Science, Abrar University, Mogadishu, Somalia.
Department of Internal Medicine, University of Health Sciences Turkey, Mogadishu Somalia-Turkey Recep Tayyip Erdoğan Training and Research Hospital, Mogadishu, Somalia.
出版信息
Int J Endocrinol. 2021 Dec 26;2021:7154250. doi: 10.1155/2021/7154250. eCollection 2021.
BACKGROUND
Thyroid disorder is one of the most common noncommunicable diseases worldwide and neglected public health issues in Somalia. The aim of the study thus was to investigate the thyroid disorders in patients attending to the largest tertiary referral hospital in Somalia.
METHODS
This retrospective study was conducted on patients admitted to the internal department of Somalia Mogadishu-Turkey Education and Research Hospital, Somali, between January 2017 and December 2019. Patients who were tested for thyroid function tests and had complete data were included. Patients with incomplete data and currently treated for any thyroid disorder were excluded from the study. Abstracted data including patients' sociodemographic characteristics, thyroid function tests, and histopathological findings were retrieved from the hospital database system.
RESULTS
A total of 976 patients with thyroid disorders were enrolled, of whom 66.6% ( = 650) were female and 33.4% ( = 326) were male. The mean age of the patients was 47 ± 18.5 years. The majority of the patients were reported in the 31-50 (35.9%) age range. The most reported thyroid function disorders were 58.8% euthyroid sick syndrome followed by 15.4% hypothyroidism, 12.5% subclinical hypothyroidism, 7.6% hyperthyroidism, and 5.7% subclinical hyperthyroidism. The distribution of comorbidity indicated that 13.4% had diabetes mellitus, 10.4% had HIV, 4.9% had malaria, and 4.5% had HIV and malaria coinfection. Thyroid malignancies were detached in 22 (2.2%) patients including eleven papillary thyroid cancer, nine patients had follicular thyroid cancer, and two patients had differentiated thyroid cancer.
CONCLUSIONS
Euthyroid sick syndrome was the most common type of thyroid disease in our setup. Hypothyroidism is the second most common, followed by subclinical hypothyroidism. Papillary thyroid cancer was the predominant histology among thyroid malignancies, followed by follicular thyroid cancer. This study revealed that thyroid diseases emerge as an important endocrine disorder encountered in Somali, necessitating a major public health response.
背景
甲状腺疾病是全球最常见的非传染性疾病之一，也是索马里被忽视的公共卫生问题。因此，本研究的目的是调查在索马里最大的三级转诊医院就诊的患者中的甲状腺疾病情况。
方法
本回顾性研究对2017年1月至2019年12月期间在索马里摩加迪沙-土耳其教育与研究医院内科住院的患者进行。纳入接受过甲状腺功能测试且数据完整的患者。数据不完整以及目前正在接受任何甲状腺疾病治疗的患者被排除在研究之外。从医院数据库系统中检索包括患者社会人口学特征、甲状腺功能测试和组织病理学检查结果在内的摘要数据。
结果
共纳入976例甲状腺疾病患者，其中66.6%（n = 650）为女性，33.4%（n = 326）为男性。患者的平均年龄为47±18.5岁。大多数患者年龄在31 - 50岁之间（35.9%）。报告最多的甲状腺功能障碍是甲状腺功能正常的病态综合征，占58.8%，其次是甲状腺功能减退，占15.4%，亚临床甲状腺功能减退占12.5%，甲状腺功能亢进占7.6%，亚临床甲状腺功能亢进占5.7%。合并症分布显示，13.4%患有糖尿病，10.4%患有艾滋病毒，4.9%患有疟疾，4.5%患有艾滋病毒和疟疾合并感染。22例（2.2%）患者发现甲状腺恶性肿瘤，其中11例为乳头状甲状腺癌，9例为滤泡状甲状腺癌，2例为分化型甲状腺癌。
结论
在我们的研究中，甲状腺功能正常的病态综合征是最常见的甲状腺疾病类型。甲状腺功能减退是第二常见的，其次是亚临床甲状腺功能减退。乳头状甲状腺癌是甲状腺恶性肿瘤中最主要的组织学类型，其次是滤泡状甲状腺癌。本研究表明，甲状腺疾病已成为索马里常见的重要内分泌疾病，需要采取重大的公共卫生应对措施。
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