Adani Abdulkamil Abdullahi, Siyad Mohamed Osman, Adan Abdisamad Mohamed, Jeele Mohamed Osman Omar
Department of Internal Medicine, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia.
Int J Gen Med. 2023 Mar 9;16:905-913. doi: 10.2147/IJGM.S403950. eCollection 2023.
In recent decades, the relationship between thyroid and kidney disease has drawn considerable attention. We aim to assess the prevalence and the determinants of hypothyroidism in hemodialysis patients in Somalia.
This is a cross-sectional study which was conducted in the hemodialysis unit of Mogadishu Somalia Turkish Training and Research Hospital, between June 1 and July, 31 2022. A total of 301 patients who are routinely going to hemodialysis were included in the study. Demographic data including age, gender, and data regarding hemodialysis were extracted from hospital information system (HIS). All participants had their thyroid function test measured before hemodialysis sessions.
A total of 301 patients were examined. Their ages ranged from 40 to 66 years, with the median age being 54 (IQR= 40-66). Males were 167 (55.5%) compared to females 134 (44.5%). Hypertension was the most common comorbidity among the patients with 137 (45.5%). Diabetic kidney disease was the most common cause of renal failure in 138 patients (45.84%) followed by hypertensive kidney disease 100 (33.22%). The prevalence rate of hypothyroidism in hemodialysis patients in our study was 28%. In hypothyroidism patients 57.8% had subclinical hypothyroidism and 42.2% had overt hypothyroidism. 70.8% of our patients were in euthyroid status. Subclinical hypothyroidism was commonly seen in patients with diabetes, hypertension, and heart disease. We found that increasing age, decreased albumin level were related to higher risk of subclinical hypothyroidism. We also found that increasing creatinine levels were associated with lower risk of overt hypothyroidism.
The prevalence rate of hypothyroidism in hemodialysis patients was 28%, with 57.8% showing subclinical hypothyroidism and 42.2% overt hypothyroidism. Increased age and low albumin level was associated with the prevalence of subclinical hypothyroidism in hemodialysis patients. Also low creatinine level was observed in overt hypothyroidism patients.
近几十年来，甲状腺与肾脏疾病之间的关系备受关注。我们旨在评估索马里血液透析患者甲状腺功能减退症的患病率及其决定因素。
这是一项横断面研究，于2022年6月1日至7月31日在索马里摩加迪沙土耳其培训与研究医院的血液透析科进行。共有301名常规进行血液透析的患者纳入本研究。从医院信息系统（HIS）中提取包括年龄、性别等人口统计学数据以及血液透析相关数据。所有参与者在血液透析前均进行了甲状腺功能测试。
共检查了301名患者。他们的年龄在40至66岁之间，中位年龄为54岁（四分位间距=40 - 66）。男性167人（55.5%），女性134人（44.5%）。高血压是患者中最常见的合并症，有137人（45.5%）。糖尿病肾病是138例患者（45.84%）肾衰竭的最常见原因，其次是高血压肾病100例（33.22%）。我们研究中血液透析患者甲状腺功能减退症的患病率为28%。在甲状腺功能减退症患者中，57.8%为亚临床甲状腺功能减退症，42.2%为显性甲状腺功能减退症。70.8%的患者甲状腺功能正常。亚临床甲状腺功能减退症常见于糖尿病、高血压和心脏病患者。我们发现年龄增加、白蛋白水平降低与亚临床甲状腺功能减退症的较高风险相关。我们还发现肌酐水平升高与显性甲状腺功能减退症的较低风险相关。
血液透析患者甲状腺功能减退症的患病率为28%，其中57.8%为亚临床甲状腺功能减退症，42.2%为显性甲状腺功能减退症。年龄增加和白蛋白水平低与血液透析患者亚临床甲状腺功能减退症的患病率相关。此外，显性甲状腺功能减退症患者的肌酐水平较低。
