State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, 510060, China.
Vesber Vitreous Institute, Guangzhou, 510060, China.
BMC Ophthalmol. 2024 Sep 20;24(1):412. doi: 10.1186/s12886-024-03646-9.
This study aimed to precisely predict the size and silicone oil injection of a foldable capsular vitreous body (FCVB) via computerized three-dimensional (3D) ocular reconstruction in the treatment of severe retinal detachment in China.
The 3D software Unigraphics NX was applied to determine the volume of the inner cavity with 16-30 mm axial length, assigning the anterior and posterior chambers, the FCVB sizes, and the silicone oil injection volume, and modeling the data between the axial length and the FCVB size. In clinical practice, IOL Master was applied to accurately measure the axial length of the contralateral healthy eye to anchor the anterior-posterior and horizontal diameters of the operated eye in horizontal position CT, and compared with the model to recommend the FCVB size and silicone oil amount, and the clinical effect was validated in cases across five hospitals in China.
For the axial length of 16-30 mm, the volume of the inner cavity is 1.2 ml-8.4 ml. FCVB size and silicone oil volume were recommended based on this volume of the inner cavity. Of 253 cases, we noted 11 cases implanted with AV-10P and 1.05 ± 0.21 ml of silicone oil, 41 with AV-12P and 1.58 ± 0.18 ml of silicone oil, 163 with AV-13.5P and 2.48 ± 0.29 ml of silicone oil, 31 with AV-15P and 3.57 ± 0.39 ml of silicone oil, and 7 with AV-17P and 5.71 ± 0.81 ml of silicone oil. There was no significant difference in postoperative visual acuity scores compared with preoperative (P = 0.097), postoperative IOP(10.29 ± 0.57mmHg)was slightly higher than preoperative IOP (9.76 ± 0.48 mmHg), but there was still no statistically significant difference between the two comparisons (P = 0.405).
Three-dimensional reconstruction prediction is a good solution for eyeballs with obvious individualized changes in severe retinal detachment, and this method helps doctors standardize FCVB size selection and the silicone oil amount for patients.
本研究旨在通过计算机化三维（3D）眼部重建，精确预测中国严重视网膜脱离患者折叠式囊玻璃体（FCVB）的大小和硅油注射量。
使用 Unigraphics NX 3D 软件确定轴向长度为 16-30mm 的眼内腔体积，分配前房和后房、FCVB 大小和硅油注射量，并对轴长与 FCVB 大小之间的数据进行建模。在临床实践中，使用 IOL Master 准确测量对侧健康眼的轴向长度，以固定手术眼的前后径和水平位 CT 中的水平直径，并与模型进行比较，推荐 FCVB 大小和硅油量，在来自中国五家医院的病例中验证临床效果。
对于 16-30mm 的轴长，眼内腔体积为 1.2ml-8.4ml。根据内腔体积推荐 FCVB 大小和硅油量。在 253 例病例中，我们发现 11 例植入 AV-10P 和 1.05±0.21ml 硅油，41 例植入 AV-12P 和 1.58±0.18ml 硅油，163 例植入 AV-13.5P 和 2.48±0.29ml 硅油，31 例植入 AV-15P 和 3.57±0.39ml 硅油，7 例植入 AV-17P 和 5.71±0.81ml 硅油。术后视力评分与术前相比无显著差异（P=0.097），术后眼压（10.29±0.57mmHg）略高于术前眼压（9.76±0.48mmHg），但两者比较仍无统计学差异（P=0.405）。
三维重建预测是严重视网膜脱离眼球明显个体化变化的良好解决方案，该方法有助于医生规范 FCVB 大小选择和患者硅油用量。
