Saifee Y, Bhatia S, Chamania C S, Salgia P, Kriplani J, Sepaha A
Department of Urology, Choithram Hospital and Research Centre, Indore, Madhya Pradesh, India.
Int J Organ Transplant Med. 2021;12(1):23-31.
Laparoscopic live donor nephrectomy (LLDN) has become the standard of care and is popular among most of the transplant centers across the globe. Despite proven advantages of LLDN, some transplantation centers hesitate to start the program because of issues concerning donor safety and allograft function.
To discusses the main barriers for creating a successful LLDN program, strategies that allowed us to start a successful LLDN program along with the study results.
The donors undergoing LLDN from December 2016 to February 2018 were enrolled in the study and prospectively evaluated. LLDN were performed by two senior surgeons alternately with assistance by the laparoscopic urologist in all cases. Also, in the present study, two technical alterations were done in the standard surgical technique of transperitoneal LDN. The first important modification made was the use of two additional ports for use by laparoscopic urologists. The second modification involved dissection on both poles of the kidney before hilar dissection.
A total of 112 transperitoneal LLDN were performed during the study period. The mean (range) of operation time was 117.5 (81-158) min; the ischemia time was 194 (171-553) sec. Only one patient needed conversion to open surgery. No other major peri-operative or posto-perative complications occurred. All kidney grafts were functioning well.
With proper planning, team approach, and few technical modifications, introduction of LLDN is safe and effective.
腹腔镜活体供肾切除术(LLDN)已成为治疗的标准方法,在全球大多数移植中心都很受欢迎。尽管LLDN已被证明具有优势,但一些移植中心由于供体安全和移植肾功能等问题,对开展该项目仍持犹豫态度。
探讨建立成功的LLDN项目的主要障碍、使我们能够启动成功的LLDN项目的策略以及研究结果。
纳入2016年12月至2018年2月接受LLDN的供体并进行前瞻性评估。所有病例的LLDN均由两名资深外科医生交替进行,腹腔镜泌尿外科医生协助。此外,在本研究中,对经腹LDN的标准手术技术进行了两项技术改进。第一个重要改进是增加了两个供腹腔镜泌尿外科医生使用的端口。第二个改进是在肾门解剖之前先对肾脏两极进行解剖。
研究期间共进行了112例经腹LLDN。平均手术时间(范围)为117.5(81 - 158)分钟;缺血时间为194(171 - 553)秒。只有1例患者需要转为开放手术。未发生其他重大围手术期或术后并发症。所有肾移植功能良好。
通过适当的规划、团队协作方法以及少量技术改进,引入LLDN是安全有效的。