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巴贝斯虫病与人体免疫系统。

Babesiosis and the human immune system.

作者信息

Rabah Hussein, Chukkalore Divya, El-Charabaty Elie, Mobarakai Neville

机构信息

Staten Island University Hospital, Department of Medicine, New York, USA.

出版信息

IDCases. 2021 Dec 18;27:e01368. doi: 10.1016/j.idcr.2021.e01368. eCollection 2022.

DOI:10.1016/j.idcr.2021.e01368
PMID:34993053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8713127/
Abstract

Immunological phenomena have been described in infections such as infective endocarditis. However, none has been reported in the context of Babesiosis. Babesiosis is a tick-borne illness caused by the protozoa of the genus Babesia and causes infections that range from asymptomatic to severe and sometimes are fatal. This report presents the first case of ANCA/ANA positive severe babesiosis in an asplenic patient treated with repeated red blood cell exchange transfusion.

摘要

免疫现象已在诸如感染性心内膜炎等感染中有所描述。然而,在巴贝斯虫病的背景下尚未有相关报道。巴贝斯虫病是一种由巴贝斯属原生动物引起的蜱传疾病,可导致从无症状到严重甚至有时致命的感染。本报告介绍了首例在无脾患者中出现的抗中性粒细胞胞浆抗体/抗核抗体阳性的严重巴贝斯虫病,该患者接受了反复的红细胞置换输血治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2434/8713127/f549a2dddf81/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2434/8713127/f549a2dddf81/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2434/8713127/f549a2dddf81/gr1.jpg

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本文引用的文献

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Parasite burden and red blood cell exchange transfusion for babesiosis.疟原虫负荷和红细胞交换输血治疗巴贝斯虫病。
J Clin Apher. 2021 Feb;36(1):127-134. doi: 10.1002/jca.21853. Epub 2020 Nov 12.
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Deciphering -Vector Interactions.破译 - 载体相互作用
Front Cell Infect Microbiol. 2017 Sep 29;7:429. doi: 10.3389/fcimb.2017.00429. eCollection 2017.
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Post-Babesiosis Warm Autoimmune Hemolytic Anemia.巴贝虫病后自身免疫性溶血性贫血。
由……引起的先天性巴贝斯虫病大鼠选定器官的组织病理学分析
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Infective endocarditis with antineutrophil cytoplasmic antibody: report of 13 cases and literature review.伴有抗中性粒细胞胞浆抗体的感染性心内膜炎:13例报告及文献复习
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Brief report: prevalence of antineutrophil cytoplasmic antibodies in infective endocarditis.简要报告:感染性心内膜炎中抗中性粒细胞胞浆抗体的流行情况。
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Human babesiosis.人类巴贝斯虫病
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The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.莱姆病、人粒细胞无形体病和巴贝斯虫病的临床评估、治疗及预防:美国传染病学会临床实践指南
Clin Infect Dis. 2006 Nov 1;43(9):1089-134. doi: 10.1086/508667. Epub 2006 Oct 2.
10
Erythrocyte invasion by Babesia parasites: current advances in the elucidation of the molecular interactions between the protozoan ligands and host receptors in the invasion stage.巴贝斯虫寄生虫对红细胞的入侵:入侵阶段原生动物配体与宿主受体之间分子相互作用解析的当前进展
Vet Parasitol. 2006 May 31;138(1-2):22-32. doi: 10.1016/j.vetpar.2006.01.037. Epub 2006 Feb 28.