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病例报告:鼻腔上皮-肌上皮癌在正电子发射断层扫描/计算机断层扫描上具有高氟代脱氧葡萄糖摄取

Case Report: Nasal Cavity Epithelial-Myoepithelial Carcinoma With High Fluoro-D-Glucose Uptake on Positron Emission Tomography/Computed Tomography.

作者信息

Dzuko Kamga Jacques, Leclere Jean-Christophe, Uguen Arnaud, Amrane Karim, Abgral Ronan

机构信息

Department of Nuclear Medicine, University Hospital of Brest, Brest, France.

Department of Otorhinolaryngology, University Hospital of Brest, Brest, France.

出版信息

Front Med (Lausanne). 2021 Dec 21;8:664520. doi: 10.3389/fmed.2021.664520. eCollection 2021.

Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare malignant neoplasm arising most frequently in the salivary glands and exceptionally in the nasal cavity. EMC accounts for ~1-2% of salivary gland tumors. Even if the nodal and distant metastasis rates are low, tumor staging remains indicated. Here, the authors present the 2-deoxy-2-[F]fluoro-D-glucose PET-CT (F-FDG-PET/CT) study of a very rare case of biopsy-proven EMC of the left nasal cavity. This F-FDG-PET/CT was performed to stage this tumor and guide the therapeutic strategy due to an atypical high-grade presentation in immunohistochemistry. To our knowledge, this is the first case reporting such high F-FDG avidity of EMC of the nasal cavity in PET/CT.

摘要

上皮-肌上皮癌(EMC)是一种罕见的恶性肿瘤,最常发生于唾液腺,极少发生于鼻腔。EMC约占唾液腺肿瘤的1%-2%。即使淋巴结和远处转移率较低,肿瘤分期仍有必要。在此,作者展示了一例经活检证实的左鼻腔EMC的2-脱氧-2-[F]氟-D-葡萄糖PET-CT(F-FDG-PET/CT)研究。由于免疫组化表现为非典型高级别,此次F-FDG-PET/CT检查旨在对该肿瘤进行分期并指导治疗策略。据我们所知,这是首例报道鼻腔EMC在PET/CT中具有如此高的F-FDG摄取的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d12/8724132/a6d042b7f630/fmed-08-664520-g0001.jpg

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