鼻腔高级别侵袭性上皮-肌上皮癌的一种不寻常表现。
An unusual presentation of aggressive epithelial-myoepithelial carcinoma of the nasal cavity with high-grade histology.
作者信息
Park J-O, Jung C-K, Sun D-I, Kim M-S
机构信息
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
出版信息
J Laryngol Otol. 2011 Dec;125(12):1286-9. doi: 10.1017/S0022215111002222. Epub 2011 Sep 5.
BACKGROUND
Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity.
CASE REPORT
A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases.
CONCLUSION
We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.
背景
上皮-肌上皮癌是一种罕见的低级别癌，通常发生于涎腺。有少数鼻腔上皮-肌上皮癌的病例报告。我们描述了一例鼻腔侵袭性上皮-肌上皮癌的独特病例。
病例报告
一名36岁女性因左侧鼻腔肿物就诊。组织病理学评估显示为上皮-肌上皮癌，伴有明显的核异型性、频繁的核分裂象和坏死。原发切除术后15个月，肿瘤在对侧鼻腔复发。遂行上颌骨内侧切除术及放射治疗。7个月的随访显示有广泛的骨转移。
结论
我们报告了一例鼻腔罕见的具有高级别组织学特征的侵袭性上皮-肌上皮癌。
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