Lee Tjen Jhung, Wan Rahimi Wan Faizal Bin, Low Ming Yoong, Nurruddin Amin Ariff
Department of Cardiology, Institute Jantung Negara (National Heart Institute), 145, Jalan Tun Razak, 50400 Wilayah Persekutuan Kuala Lumpur, Malaysia.
Eur Heart J Case Rep. 2021 Oct 23;5(12):ytab432. doi: 10.1093/ehjcr/ytab432. eCollection 2021 Dec.
Intravascular lithotripsy is a new method used to treat calcified coronary lesions (CCLs). Percutaneous coronary intervention of CCLs has conventionally been classified as a complex procedure. In the majority of calcified cases, atherectomy is required for sufficient plaque modification prior to stent implantation. Intravascular lithotripsy has been shown to be safe and effective in clinical trials, but as worldwide usage increases, cases of complications are beginning to emerge.
We describe a 71-year-old woman, who after an episode of non-ST-elevation acute coronary syndrome underwent coronary angiography. The culprit vessel was identified to be a severely stenosed left anterior descending artery which was also heavily calcified and tortuous. Intravascular lithotripsy (IVL) was employed for calcium modification prior to stent implantation, but the IVL balloon ruptured during shockwave lithotripsy, resulting in coronary artery dissection. Subsequent management steps and stent deployment resulted in favourable angiographic results. Our findings are further detailed on optical coherence tomography, demonstrating certain features which might predispose to IVL balloon rupture.
We discuss the mechanism of action during intravascular lithotripsy, and how the shockwaves from the lithotripter modify calcified lesions, whilst keeping soft tissue unharmed. Results from clinical trials and multiple real-world studies have shown that complication rates are low. This case report aims to illustrate how the rupture of an intravascular lithotripsy balloon can result in coronary artery dissection. Optical coherence tomography can help in identifying potential anatomical features which may precede such complications.
血管内碎石术是一种用于治疗钙化冠状动脉病变(CCL)的新方法。CCL的经皮冠状动脉介入治疗传统上被归类为复杂手术。在大多数钙化病例中,在植入支架之前需要进行斑块旋切术以充分修饰斑块。血管内碎石术在临床试验中已被证明是安全有效的,但随着其在全球范围内的使用增加,并发症病例开始出现。
我们描述了一名71岁女性,在经历非ST段抬高型急性冠状动脉综合征后接受了冠状动脉造影。确定罪犯血管为严重狭窄的左前降支动脉,该动脉也严重钙化且迂曲。在植入支架之前采用血管内碎石术(IVL)进行钙化修饰,但在冲击波碎石术期间IVL球囊破裂,导致冠状动脉夹层。随后的处理步骤和支架置入产生了良好的血管造影结果。我们的发现通过光学相干断层扫描进一步详细说明,显示了某些可能易导致IVL球囊破裂的特征。
我们讨论了血管内碎石术期间的作用机制,以及碎石器产生的冲击波如何修饰钙化病变,同时使软组织不受损伤。临床试验和多项真实世界研究的结果表明并发症发生率较低。本病例报告旨在说明血管内碎石术球囊破裂如何导致冠状动脉夹层。光学相干断层扫描有助于识别可能先于此类并发症出现的潜在解剖特征。