Vanegas-Arroyave Nora, Chen Denise F, Lauro Peter M, Norato Gina, Lungu Codrin, Hallett Mark
Department of Neurology, Baylor College of Medicine, Houston, Texas, USA.
Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
Mov Disord. 2022 Apr;37(4):864-869. doi: 10.1002/mds.28917. Epub 2022 Jan 8.
Parkinson's disease (PD) is associated with gait and visuomotor abnormalities, but it is not clear where PD patients look during ambulation.
We sought to characterize the visual areas of interest explored by PD patients, with and without freezing of gait (FOG), compared to healthy volunteers (HVs).
Using an eye-tracking device, we compared visual fixation patterns in 17 HVs and 18 PD patients, with and without FOG, during an ambulatory and a nonambulatory, computer-based task.
During ambulation, PD patients with FOG fixated more on proximal areas of the ground and less on the target destination. PD patients without FOG displayed a fixation pattern more similar to that of HVs. Similar patterns were observed during the nonambulatory, computer-based task.
Our findings suggest increased dependence on visual feedback from nearby areas in the environment in PD patients with FOG, even in the absence of motor demands. © 2022 International Parkinson and Movement Disorder Society.
帕金森病（PD）与步态和视觉运动异常有关，但尚不清楚PD患者在行走过程中注视的位置。
我们试图描述PD患者（有和没有冻结步态[FOG]）与健康志愿者（HV）相比所探索的视觉感兴趣区域。
使用眼动追踪设备，我们比较了17名HV和18名有和没有FOG的PD患者在动态和非动态的基于计算机的任务中的视觉注视模式。
在行走过程中，有FOG的PD患者更多地注视地面的近端区域，而较少注视目标目的地。没有FOG的PD患者表现出与HV更相似的注视模式。在非动态的基于计算机的任务中也观察到了类似的模式。
我们的研究结果表明，即使在没有运动需求的情况下，有FOG的PD患者对来自环境中附近区域的视觉反馈的依赖性增加。© 2022国际帕金森和运动障碍协会。
