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非 ST 段抬高型急性冠脉综合征患者行非选择性经皮冠状动脉介入治疗后当日出院。

Same day discharge following non-elective PCI for non-ST elevation acute coronary syndromes.

机构信息

Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland OH.

Advocate Christ Medical Center/University of Illinois at Chicago, Oak Lawn, IL; Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA.

出版信息

Am Heart J. 2022 Apr;246:125-135. doi: 10.1016/j.ahj.2021.12.015. Epub 2022 Jan 6.

Abstract

BACKGROUND AND AIM

Timing of discharge after percutaneous coronary intervention (PCI) is a crucial aspect of procedural safety and patient turnover. We examined predictors and outcomes of same-day discharge (SDD) after non-elective PCI for non-ST elevation acute coronary syndromes (NSTE-ACS) in comparison with next-day discharge (NDD).

METHODS

Baseline demographic, clinical, and procedural data were collected as were in-hospital outcomes and post-PCI length of stay (LOS) for all patients undergoing non-elective PCI for NSTE-ACS between 2011 and 2014 at a central tertiary care center. Thirty day and 1-year mortality and bleeding as well as 30-day readmission rates were determined from social security record and medical chart review. Logistic regression was performed to identify predictors of SDD, and propensity-matched analysis was done to examine the differences in outcomes between NDD and SDD.

RESULTS

Out of 2,529 patients who underwent non-elective PCI for NSTE-ACS from 2011 to 2014, 1,385 met the inclusion criteria (mean age = 63 years; 26% women) and were discharged either the same day of (N = 300) or the day after (N = 1,085) PCI. Thirty-day and one-year mortality and major bleeding rates were similar between the 2 groups. Logistic regression identified male sex, radial access, negative troponin biomarker status, and procedure start time as predictors of SDD. In propensity-matched analyses, there was no difference in 30-day mortality and readmission between SDD and NDD groups.

CONCLUSIONS

SDD after non-elective PCI for NSTE-ACS may be a reasonable alternative to NDD for selected low-risk patients with comparable mortality, bleeding, and readmission rates.

摘要

背景与目的

经皮冠状动脉介入治疗(PCI)后出院时间是程序安全性和患者周转率的关键方面。我们比较了非 ST 段抬高型急性冠状动脉综合征(NSTE-ACS)患者行非紧急 PCI 后的当日出院(SDD)与次日出院(NDD)的预测因素和结局。

方法

收集了 2011 年至 2014 年在一个中心三级护理中心因 NSTE-ACS 行非紧急 PCI 的所有患者的基线人口统计学、临床和手术数据,以及住院期间的结局和 PCI 后住院时间(LOS)。通过社会安全记录和病历回顾确定 30 天和 1 年死亡率和出血以及 30 天再入院率。采用逻辑回归确定 SDD 的预测因素,并进行倾向评分匹配分析以检查 NDD 和 SDD 之间结局的差异。

结果

在 2011 年至 2014 年因 NSTE-ACS 行非紧急 PCI 的 2529 例患者中,有 1385 例符合纳入标准(平均年龄 63 岁;26%为女性),他们分别在 PCI 当天(N=300)或第二天(N=1085)出院。两组的 30 天和 1 年死亡率和大出血率相似。逻辑回归确定男性、桡动脉入路、阴性肌钙蛋白生物标志物状态和手术开始时间为 SDD 的预测因素。在倾向评分匹配分析中,SDD 和 NDD 组之间 30 天死亡率和再入院率无差异。

结论

对于选择的低风险患者,非 ST 段抬高型急性冠状动脉综合征患者行非紧急 PCI 后 SDD 可能是 NDD 的合理替代方案,其死亡率、出血率和再入院率相似。

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