Department of Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Department of Cardiology, Public Hospital Klagenfurt am Woerthersee, Klagenfurt am Woerthersee, Austria.
Wien Klin Wochenschr. 2024 May;136(Suppl 3):44-60. doi: 10.1007/s00508-024-02347-z. Epub 2024 May 14.
Percutaneous coronary intervention is a well-established revascularization strategy for patients with coronary artery disease. The safety and feasibility of performing these procedures on a same-day discharge basis for selected patients has been studied in a large number of mostly nonrandomized trials. An up to date literature review should focus on trials with radial access, representing the current standard for coronary procedures in Austria and other European countries.
The aim of this consensus statement is to review the most recent evidence for the safety and feasibility of performing same-day discharge procedures in selected patients. A structured literature search was performed using prespecified search criteria, focusing on trials with radial access procedures.
A total of 44 clinical trials and 4 large meta-analyses were retrieved, spanning 21 years of clinical evidence from 2001 to 2022. The outcome data from a wide range of clinical settings were unanimous in showing no negative effect on early (24 h) or late (30 day) major adverse events after same-day discharge coronary procedures. Based on nine prospective trials a comprehensive meta-analysis was compiled. Using 1‑month major adverse events data the pooled odds ratio of same-day discharge versus overnight stay procedures was 0.66 (95% confidence interval, CI 0.35-01.24; p = 0.19; I 0%), indicating a noninferiority in carefully selected patients.
Outcome data from same-day discharge coronary intervention trials with radial access confirm the robust safety profile showing no increase in the risk of major adverse events compared to overnight stay.
经皮冠状动脉介入治疗是冠心病患者一种成熟的血运重建策略。大量非随机试验研究了为选定患者在同一天出院的基础上进行这些手术的安全性和可行性。最新文献综述应侧重于使用桡动脉入路的试验,桡动脉入路代表了目前奥地利和其他欧洲国家进行冠状动脉手术的标准。
本共识声明的目的是回顾在选定患者中进行同一天出院手术的最新安全性和可行性证据。使用预设的搜索标准进行了结构化文献搜索,重点关注桡动脉入路的试验。
共检索到 44 项临床试验和 4 项大型荟萃分析,涵盖了 2001 年至 2022 年 21 年的临床证据。来自各种临床环境的结果数据一致表明,同一天出院的冠状动脉手术后,早期(24 小时)或晚期(30 天)主要不良事件没有负面影响。基于 9 项前瞻性试验,进行了综合荟萃分析。使用 1 个月的主要不良事件数据,同一天出院与过夜留观手术的汇总优势比为 0.66(95%置信区间,0.35-01.24;p=0.19;I 0%),表明在精心选择的患者中具有非劣效性。
使用桡动脉入路的同一天出院冠状动脉介入治疗试验的结果数据证实了其安全性能良好,与过夜留观相比,主要不良事件的风险没有增加。