De Reuck J, De Coster W, vander Eecken H
Acta Neuropathol. 1978 May 24;42(2):141-4. doi: 10.1007/BF00690981.
The gastrocnemius muscles of 3 groups of 10 rats, sacrified 5, 7, and 12 days respectively, following tenotomy, were submitted to different types of fixation, fixative and embedding. The occurrence of target fibres is shown not to be an artefact due to the histological procedures. Further examination demonstrates that the target phenomenon occurs in the shortest fibres on the medial side of both heads of the gastrocnemius muscle and that it consists mainly of a disarrangement of the contractile elements of the muscle fibres. This study argues that this phenomenon represents some kind of myotonic state of a pathological muscle.
分别在跟腱切断术后5天、7天和12天处死的3组大鼠（每组10只）的腓肠肌，接受了不同类型的固定、固定剂和包埋处理。研究表明，目标纤维的出现并非组织学程序导致的假象。进一步检查发现，目标现象出现在腓肠肌两头内侧最短的纤维中，且主要由肌纤维收缩成分的排列紊乱组成。该研究认为，这种现象代表了病理性肌肉的某种强直性状态。
