Suppr超能文献

探讨亲密伴侣暴力和虐待对年轻人抑郁症状的因果作用:一项基于人群的队列研究。

Exploring the causal role of intimate partner violence and abuse on depressive symptoms in young adults: a population-based cohort study.

机构信息

Department of Population Health Sciences, University of Bristol, Bristol, UK.

MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

出版信息

BMC Med. 2022 Jan 10;20(1):1. doi: 10.1186/s12916-021-02182-3.

Abstract

BACKGROUND

Previous studies have shown an association between experience of intimate partner violence and abuse (IPVA) and depression. Whether this is a causal relationship or explained by prior vulnerability that influences the risk of both IPVA and depression is not known.

METHODS

We analysed data from the Avon Longitudinal Study of Parents and Children prospective cohort (N = 1764 women, 1028 men). To assess the causal association between IPVA at 18-21 years old and logged depressive symptom scores at age 23, we used (i) multivariable linear regression, (ii) inverse probability of treatment weighting (IPTW), and (iii) difference-in-difference (DiD) analysis, which compared the mean change in logged depressive symptom scores between ages 16 and 23 between those who experienced IPVA and those who did not.

RESULTS

Women who experienced IPVA had on average 26% higher depressive symptom scores after adjustment for measured confounders (ratio of geometric means 1.26, 95% CI 1.13 to 1.40). In men, the difference was 5% (ratio of geometric means 1.05, 95% CI 0.92 to 1.21). Results from IPTW analysis were similar. In the DiD analysis, there was no evidence that being exposed to IPVA affected the change in depressive symptom scores over time compared to being in the non-exposed group for either women (difference-in-differences 1%, -12 to 16%) or men (-1%, -19 to 20%).

CONCLUSIONS

Multivariable linear regression and IPTW suggested an association between IPVA and higher depressive symptom score in women but not men, but DiD analysis indicated a null effect in both women and men. This suggests the causal origins of higher depressive symptoms in this young adult population are likely to reflect prior vulnerability that leads to both higher depressive symptoms and increased risk of IPVA exposure.

摘要

背景

先前的研究表明,亲密伴侣暴力和虐待(IPVA)经历与抑郁之间存在关联。但目前尚不清楚这种关联是因果关系,还是由先前的脆弱性导致的,而这种脆弱性会影响 IPVA 和抑郁的双重风险。

方法

我们分析了阿冯纵向研究父母和孩子前瞻性队列(N=1764 名女性,1028 名男性)的数据。为了评估 18-21 岁时 IPVA 与 23 岁时记录的抑郁症状评分之间的因果关系,我们使用了(i)多变量线性回归,(ii)逆概率治疗加权(IPTW)和(iii)差值(DiD)分析,该分析比较了经历过 IPVA 和未经历过 IPVA 的个体在 16 岁至 23 岁之间记录的抑郁症状评分的平均变化。

结果

在调整了测量混杂因素后,经历过 IPVA 的女性的抑郁症状评分平均高出 26%(几何均数比 1.26,95%CI 1.13 至 1.40)。在男性中,差异为 5%(几何均数比 1.05,95%CI 0.92 至 1.21)。IPTW 分析结果相似。在 DiD 分析中,与未暴露组相比,暴露于 IPVA 并未显示出对女性(差异的差异为 1%,-12 至 16%)或男性(-1%,-19 至 20%)随时间变化的抑郁症状评分产生影响。

结论

多变量线性回归和 IPTW 表明 IPVA 与女性较高的抑郁症状评分之间存在关联,但与男性无关,但 DiD 分析表明女性和男性均无明显影响。这表明,在这个年轻的成年人群体中,较高的抑郁症状的因果起源可能反映了先前的脆弱性,这种脆弱性既导致了较高的抑郁症状,又增加了 IPVA 暴露的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8330/8744329/1e24f575fb6f/12916_2021_2182_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验