Sangvatanakul Paradi, Tangthianchaichana Jakkree, Tasanarong Adis, Pabalan Noel, Tharabenjasin Phuntila
Cooperative Learning Center, Chulabhorn International College of Medicine, and Faculty of Medicine, Thammasat University, Klong Luang, Rangsit, Pathumthani, Thailand.
Nephrology Unit, Faculty of Medicine, Thammasat University, Klong Luang, Rangsit, Pathumthani, Thailand.
Med Acupunct. 2021 Oct 1;33(5):335-342. doi: 10.1089/acu.2020.1490. Epub 2021 Oct 18.
Myopia prevalence mostly affects young people, particularly in Asia. Of the several recommendations addressing the myopia epidemic, auricular acupoint stimulation (AAS) has been proposed and investigated. However, reported outcomes have been inconsistent, prompting a meta-analysis to obtain more precise estimates. Twelve articles were included in a meta-analysis, wherein each article was evaluated for risk of bias. Summary effects were calculated using odds ratios () and 95% confidence intervals (CIs). Outlier and sensitivity treatments as well as publication bias assessment were applied. Risk of bias among the articles was low in random sequence but generally unclear judgments for the other bias criteria. AAS outcomes were significant ( [-value for association] <0.00001-0.003) when random and fixed effects favored the treated groups ( 2.87-3.42; 95% CIs: 1.44-5.75). This meta-analysis showed evidence of AAS being effective for controlling myopia. Substantial magnitude (up to 3.4-fold), robustness, and lack of bias strengthened this effect.
近视患病率主要影响年轻人，尤其是在亚洲。在针对近视流行的多项建议中，耳穴刺激（AAS）已被提出并进行了研究。然而，报告的结果并不一致，因此进行了一项荟萃分析以获得更精确的估计。一项荟萃分析纳入了12篇文章，其中每篇文章都评估了偏倚风险。使用比值比（OR）和95%置信区间（CI）计算汇总效应。应用了异常值和敏感性处理以及发表偏倚评估。文章之间的随机序列偏倚风险较低，但对于其他偏倚标准的判断总体上不明确。当随机效应和固定效应有利于治疗组时（OR = 2.87 - 3.42；95% CI：1.44 - 5.75），耳穴刺激的结果具有显著性（关联P值<0.00001 - 0.003）。这项荟萃分析表明有证据支持耳穴刺激对控制近视有效。较大的效应量（高达3.4倍）、稳健性以及无偏倚性强化了这一效果。
