Giuggioli Dilia, Magnani Luca, Spinella Amelia, Bajocchi Gianluigi, Palermo Adalgisa, Lumetti Federica, Cocchiara Emanuele, Salvarani Carlo
Scleroderma Unit, University of Modena and Reggio Emilia.
Rheumatology Unit, AUSL-IRCCS of Reggio Emilia, Italy.
Dermatol Reports. 2021 Oct 5;13(3):9075. doi: 10.4081/dr.2021.9075. eCollection 2021 Nov 17.
Systemic sclerosis (SSc) is a complex autoimmune and up to 50% of patients develop digital ulcers. We revised fifty consecutive patients with SSc-related digital ulcers (DUs) who referred to our Scleroderma Unit. Thirty-five of them who showed clear signs of DUs infection underwent to cutaneous swab and microbiological data collection. We performed 87 cutaneous swabs overall. DUs were recurrent in 58% of the patients and multiple in 60% of patients. Fourty-four swabs (53%) were positive for (13% Methicillin-Resistant), 9 (10%) were positive for , and then the others less frequently isolated. Nine patients (25%) needed hospitalization. Our data support a patient-tailored approached to DUs, particularly those infected. Selfhygiene and asepsis during dressing procedures are mandatory. Patient must be trained to avoid dangerous behaviors and reduce the risk of infection.
系统性硬化症（SSc）是一种复杂的自身免疫性疾病，高达50%的患者会出现指端溃疡。我们回顾了连续50例转诊至我们硬皮病科的与SSc相关的指端溃疡（DU）患者。其中35例有明确DU感染迹象的患者接受了皮肤拭子检查并收集了微生物学数据。我们总共进行了87次皮肤拭子检查。58%的患者DU复发，60%的患者为多发。44份拭子（53%）检测到[具体细菌名称未给出]阳性（耐甲氧西林的占13%），9份（10%）检测到[具体细菌名称未给出]阳性，其他细菌检出频率较低。9名患者（25%）需要住院治疗。我们的数据支持针对DU患者，尤其是感染患者采取个性化的治疗方法。换药过程中的自我卫生和无菌操作是必需的。必须对患者进行培训，以避免危险行为并降低感染风险。
