• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项评估罗马尼亚西南部一个城市婴幼儿甲状腺功能的横断面研究。

A Cross-Sectional Study to Assess Thyroid Function in Infants and Children in a City from South-Western Romania.

作者信息

Vasile Corina Maria, Ghenea Alice Elena, Udriştoiu Anca Loredana, Udriştoiu Ştefan, Popescu Mihaela, Padureanu Vlad, Alexandru Dragoş Ovidiu

机构信息

PhD School, University of Medicine and Pharmacy of Craiova, Romania.

Department of Pediatric Cardiology, County Clinical Emergency Hospital of Craiova, Romania.

出版信息

Curr Health Sci J. 2021 Jul-Sep;47(3):420-427. doi: 10.12865/CHSJ.47.03.13. Epub 2021 Sep 30.

DOI:10.12865/CHSJ.47.03.13
PMID:35003775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8679162/
Abstract

Thyroid hormones are critical regulators of growth, myelination of the nervous system, metabolism, and organ function. The most prevalent endocrinopathies in childhood are related to thyroid disorders. Thyroid problems in children and adolescents have a significantly different etiology and clinical presentation than in adults. Thus, pediatric medical care involves an understanding of the unique features of thyroid function and dysfunction during childhood and adolescence. The etiology and clinical manifestations of thyroid disorders in children and adolescents are vastly different from those in adults. The particular aspects of thyroid function and malfunction in childhood and adolescence are hence part of pediatric medical therapy. To prevent persistent nervous system damage and developmental problems, it is vital to recognize and treat thyroid dysfunction in neonates as early as possible. The purpose of the research was to understand more how children's thyroid problems function, structure, and prevalence. The research examined 30 children under the age of 16 years who had symptoms that were linked to thyroid problems. In addition to demographic and family information, thyroid ultrasounds and blood samples for the detection of T3, T4, and TSH were obtained. Females surpassed males by a small majority (2.33:1 ratio).Out of the total children included in the study, 14(46.7%) cases for autoimmune thyroiditis, 2(6.67%) cases for congenital hypothyroidism, 1(3.33%) case for hyperthyroidism, 1(3.33%) case for hyperthyroidism-Graves disease, 8(26.7%) cases for hypothyroidism and 4(13.3%) cases for subclinical hypothyroidism.

摘要

甲状腺激素是生长、神经系统髓鞘形成、新陈代谢及器官功能的关键调节因子。儿童期最常见的内分泌疾病与甲状腺紊乱有关。儿童和青少年的甲状腺问题在病因和临床表现上与成人有显著差异。因此,儿科医疗需要了解儿童期和青春期甲状腺功能及功能障碍的独特特征。儿童和青少年甲状腺疾病的病因和临床表现与成人有很大不同。儿童期和青春期甲状腺功能及功能异常的特殊方面因此是儿科医疗的一部分。为防止持续的神经系统损伤和发育问题,尽早识别和治疗新生儿甲状腺功能障碍至关重要。该研究的目的是更深入了解儿童甲状腺问题的功能、结构和患病率。该研究检查了30名16岁以下有与甲状腺问题相关症状的儿童。除了人口统计学和家庭信息外,还进行了甲状腺超声检查并采集了血液样本以检测T3、T4和TSH。女性略多于男性(比例为2.33:1)。在纳入研究的儿童总数中,自身免疫性甲状腺炎14例(46.7%),先天性甲状腺功能减退症2例(6.67%),甲状腺功能亢进症1例(3.33%),格雷夫斯病甲状腺功能亢进症1例(3.33%),甲状腺功能减退症8例(26.7%),亚临床甲状腺功能减退症4例(13.3%)。

相似文献

1
A Cross-Sectional Study to Assess Thyroid Function in Infants and Children in a City from South-Western Romania.一项评估罗马尼亚西南部一个城市婴幼儿甲状腺功能的横断面研究。
Curr Health Sci J. 2021 Jul-Sep;47(3):420-427. doi: 10.12865/CHSJ.47.03.13. Epub 2021 Sep 30.
2
Thyroid disorders in children from birth to adolescence.从出生到青春期儿童的甲状腺疾病
Eur J Nucl Med Mol Imaging. 2002 Aug;29 Suppl 2:S439-46. doi: 10.1007/s00259-002-0905-3. Epub 2002 Jul 3.
3
No Effect of Thyroid Dysfunction and Autoimmunity on Health-Related Quality of Life and Mental Health in Children and Adolescents: Results From a Nationwide Cross-Sectional Study.甲状腺功能障碍和自身免疫对儿童和青少年健康相关生活质量和心理健康的影响:来自全国性横断面研究的结果。
Front Endocrinol (Lausanne). 2020 Sep 2;11:454. doi: 10.3389/fendo.2020.00454. eCollection 2020.
4
A Cross-Sectional Study to Assess the Prevalence of Adult Thyroid Dysfunction Disorders in Jordan.横断面研究评估约旦成人甲状腺功能障碍疾病的患病率。
Thyroid. 2019 Aug;29(8):1052-1059. doi: 10.1089/thy.2018.0579. Epub 2019 Jul 1.
5
Congenital Anomalies in Infant With Congenital Hypothyroidism: A Review of Pathogenesis, Diagnostic Options, and Management Protocols.先天性甲状腺功能减退症患儿的先天性异常:发病机制、诊断方法及管理方案综述
Cureus. 2022 May 2;14(5):e24669. doi: 10.7759/cureus.24669. eCollection 2022 May.
6
[Maternal autoimmune thyroid disease: relevance for the newborn].[母体自身免疫性甲状腺疾病:对新生儿的影响]
Med Clin (Barc). 2015 Apr 8;144(7):297-303. doi: 10.1016/j.medcli.2013.10.024. Epub 2014 Jan 30.
7
[Current questions of thyroid diseases in childhood].[儿童甲状腺疾病的当前问题]
Orv Hetil. 2011 Apr 17;152(16):617-27. doi: 10.1556/OH.2011.29088.
8
[Thyroid diseases in sub-Saharan Africa].[撒哈拉以南非洲地区的甲状腺疾病]
Sante. 2007 Jan-Mar;17(1):33-9.
9
A prevalence of thyroid disorder in Western part of Nepal.尼泊尔西部甲状腺疾病的患病率。
J Clin Diagn Res. 2013 Feb;7(2):193-6. doi: 10.7860/JCDR/2013/4833.2724. Epub 2013 Feb 1.
10
Endemic infantile hypothyroidism in a severe endemic goitre area of central Africa.非洲中部严重地方性甲状腺肿地区的地方性婴儿甲状腺功能减退症
Clin Endocrinol (Oxf). 1984 Mar;20(3):327-40. doi: 10.1111/j.1365-2265.1984.tb00089.x.

本文引用的文献

1
Imaging and Imaging-Based Management of Pediatric Thyroid Nodules.小儿甲状腺结节的影像学检查及基于影像学的管理
J Clin Med. 2020 Feb 1;9(2):384. doi: 10.3390/jcm9020384.
2
Pattern of Thyroid Disorders in Children and Adolescents Seen at the Lagos University Teaching Hospital, Nigeria, Over a 10-year Period.尼日利亚拉各斯大学教学医院10年间儿童及青少年甲状腺疾病模式
Niger Med J. 2017 May-Jun;58(3):101-106. doi: 10.4103/nmj.NMJ_156_16.
3
Management of Fetal and Neonatal Graves' Disease.胎儿及新生儿格雷夫斯病的管理
Horm Res Paediatr. 2017;87(1):1-6. doi: 10.1159/000453065. Epub 2016 Dec 16.
4
Prevalence of Thyroid Disorders in Children at a Tertiary Care Hospital in Western India.印度西部一家三级护理医院儿童甲状腺疾病的患病率
J Clin Diagn Res. 2016 Feb;10(2):SC01-4. doi: 10.7860/JCDR/2016/16315.7189. Epub 2016 Feb 1.
5
Congenital hypothyroidism.先天性甲状腺功能减退症
Indian J Endocrinol Metab. 2015 Mar-Apr;19(2):221-7. doi: 10.4103/2230-8210.131748.
6
European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism.欧洲儿科内分泌学会关于先天性甲状腺功能减退症筛查、诊断和管理的共识指南。
J Clin Endocrinol Metab. 2014 Feb;99(2):363-84. doi: 10.1210/jc.2013-1891. Epub 2014 Jan 21.
7
Subclinical hypothyroidism in children and adolescents: a wide range of clinical, biochemical, and genetic factors involved.儿童和青少年亚临床甲状腺功能减退症:涉及多种临床、生化和遗传因素。
J Clin Endocrinol Metab. 2009 Jul;94(7):2414-20. doi: 10.1210/jc.2009-0375. Epub 2009 May 5.
8
Prospective evaluation of the natural course of idiopathic subclinical hypothyroidism in childhood and adolescence.儿童及青少年特发性亚临床甲状腺功能减退自然病程的前瞻性评估。
Eur J Endocrinol. 2009 Mar;160(3):417-21. doi: 10.1530/EJE-08-0625. Epub 2008 Dec 12.
9
Hyperthyrotropinemia in obese children is reversible after weight loss and is not related to lipids.肥胖儿童的促甲状腺激素血症在体重减轻后是可逆的,且与血脂无关。
J Clin Endocrinol Metab. 2006 Aug;91(8):3088-91. doi: 10.1210/jc.2006-0095. Epub 2006 May 9.
10
Management of Graves' disease during pregnancy: the key role of fetal thyroid gland monitoring.妊娠期格雷夫斯病的管理:胎儿甲状腺监测的关键作用。
J Clin Endocrinol Metab. 2005 Nov;90(11):6093-8. doi: 10.1210/jc.2004-2555. Epub 2005 Aug 23.