Alhafi Mais A, Janahi Mohamed I, Almossalli Zainab N
Dermatology, Salmaniya Medical Complex, Manama, BHR.
Orthopedic Surgery, Salmaniya Medical Complex, Manama, BHR.
Cureus. 2021 Dec 6;13(12):e20221. doi: 10.7759/cureus.20221. eCollection 2021 Dec.
Subcorneal pustular dermatosis (SPD) is a rare chronic condition rarely seen in adolescence and childhood. The exact etiology of the disease remains unknown. In this paper, we report the case of a 14-year-old girl who came with a history of itchy skin lesions confined to the upper and lower extremities, thighs and pubic area for two months. Physical examination showed well-demarcated annular brownish plaques, ranging in size from 5cm to 7cm, in addition to a scaly and elevated border with few pustules noted over the upper and lower extremities, thighs and pubic area. Some lesions also showed central clearing. New annular vesicular lesions were also noted on the lower extremity and inner thigh. She was diagnosed with SPD based on the characteristic clinical and histological features. The patient was treated with Dapsone and showed good clinical response.
角层下脓疱性皮肤病（SPD）是一种罕见的慢性疾病，在青少年和儿童中很少见。该疾病的确切病因尚不清楚。在本文中，我们报告了一名14岁女孩的病例，她有两个月的皮肤瘙痒病史，病变局限于上下肢、大腿和耻骨区。体格检查显示边界清晰的环形褐色斑块，大小从5厘米到7厘米不等，此外，上下肢、大腿和耻骨区有鳞屑状且隆起的边界，伴有少量脓疱。一些病变还显示中央消退。下肢和大腿内侧也发现了新的环形水疱性病变。根据特征性的临床和组织学特征，她被诊断为SPD。该患者接受了氨苯砜治疗，临床反应良好。
