Qi-Xian Tan, Chew-Ean Tan, Abdul Rahim Adlina, Nasaruddin Rona A
Ophthalmology, Hospital Sultanah Bahiyah, Alor Setar, MYS.
Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Cureus. 2022 Jan 4;14(1):e20922. doi: 10.7759/cureus.20922. eCollection 2022 Jan.
Background The majority of eyelid tumours are benign in nature and constitute 82%-98% of all eyelid tumours. This study aimed to explore the prevalence and frequency of histopathological diagnoses of eyelid tumours encountered in Hospital Sultanah Bahiyah (HSB), Malaysia, from 2016 to 2020. Method This study is a case series of 136 patients with eyelid tumours who underwent eyelid biopsy. Result Twenty-three (17%) patients were below 18 years old, 64 (47%) patients were between 19 and 64 years old and 49 (36%) patients were more than 65 years old. The mean age in this study was 47.9 ± 25.4 years. The most common benign eyelid tumours were dermoid cyst (31, 22.8%), melanocytic nevus (19, 14%), granuloma (17, 12.5%), squamous cell papilloma (13, 9.6%) and epidermal cyst (12, 8.8%). Most of the benign eyelid tumours occurred at the upper lids (79.8%), and most of the malignant eyelid tumours occurred at the lower lids (81.8%). The most common malignant eyelid tumours were basal cell carcinoma (BCC) (6, 14.3%), followed by malignant lymphoma (3, 6.1%) and sebaceous gland carcinoma (2, 4.1%). Eight out of nine cases of BCC were located at the lower lids. All malignant lymphomas were primary lymphoma. Five were extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT), and one was follicular lymphoma. All cases with benign and malignant tumours required only a single surgery for excision, and none of the cases had a recurrence. Conclusion There were limited references to the epidemiology of histopathological diagnoses of eyelid tumours in Malaysia. Although benign lesions comprise the majority of eyelid tumours, it is essential to delineate between benign and malignant eyelid tumours.
大多数眼睑肿瘤本质上是良性的,占所有眼睑肿瘤的82%-98%。本研究旨在探讨2016年至2020年在马来西亚苏丹娜·巴希亚医院(HSB)遇到的眼睑肿瘤组织病理学诊断的患病率和频率。方法:本研究是对136例接受眼睑活检的眼睑肿瘤患者的病例系列研究。结果:23例(17%)患者年龄在18岁以下,64例(47%)患者年龄在19至64岁之间,49例(36%)患者年龄超过65岁。本研究的平均年龄为47.9±25.4岁。最常见的良性眼睑肿瘤是皮样囊肿(31例,22.8%)、黑素细胞痣(19例,14%)、肉芽肿(17例,12.5%)、鳞状细胞乳头状瘤(13例,9.6%)和表皮样囊肿(12例,8.8%)。大多数良性眼睑肿瘤发生在上睑(79.8%),大多数恶性眼睑肿瘤发生在下睑(81.8%)。最常见的恶性眼睑肿瘤是基底细胞癌(BCC)(6例,14.3%),其次是恶性淋巴瘤(3例,6.1%)和皮脂腺癌(2例,4.1%)。9例BCC中有8例位于下睑。所有恶性淋巴瘤均为原发性淋巴瘤。5例为黏膜相关淋巴组织边缘区淋巴瘤(MALT),1例为滤泡性淋巴瘤。所有良性和恶性肿瘤病例仅需一次手术切除,且无一例复发。结论:关于马来西亚眼睑肿瘤组织病理学诊断的流行病学资料有限。虽然良性病变占眼睑肿瘤的大多数,但区分良性和恶性眼睑肿瘤至关重要。