Asproudis Ioannis, Sotiropoulos Georgios, Gartzios Christos, Raggos Vassilios, Papoudou-Bai Alexandra, Ntountas Ioannis, Katsanos Andreas, Tatsioni Athina
University Eye Clinic, Ioannina, Greece.
Department of Maxillofacial Surgery, Medical School, University of Ioannina, Ioannina, Greece.
Middle East Afr J Ophthalmol. 2015 Apr-Jun;22(2):230-2. doi: 10.4103/0974-9233.151881.
The aim was to describe the epidemiology of primary eyelid tumors over a 30-year period at the Ioannina University Eye Clinic, Greece.
This retrospective case series examined the histopathology of eyelid tumor specimens of patients treated between 1983 and 2012. Data were collected on patient age, gender, location of the lesion, extent of tumor excision and recurrence. Descriptive and inferential statistics were used to describe the study subgroups.
A total of 851 eyelid tumors comprised the study sample. There were 351 (41.2%) malignant cases and 500 (58.8%) benign cases. For malignant tumors, there were 86% basal cell carcinomas, 7% squamous cell carcinomas, and 7% basosquamous cell carcinomas. The benign eyelid lesions were comprised of 20% cysts, 18% seborrheic keratosis, 13% nevi, and 13% papillomas. Benign eyelid lesions occurred with equal frequency in the upper and lower lids. Malignant lesions were more frequently located in the lower lid. The mean age at diagnosis was 49 ± 1.45 years for patients with benign lesions and 67 ± 1.6 years for patients with malignant lesions.
In this Greek cohort, benign eyelid lesions affected mostly young individuals, and malignant lesions occurred predominantly in elderly patients. Males and females were equally affected by malignant lesions, and recurrence after surgical excision was rare.
本研究旨在描述希腊约阿尼纳大学眼科诊所30年间原发性眼睑肿瘤的流行病学特征。
本回顾性病例系列研究对1983年至2012年间接受治疗的眼睑肿瘤患者标本进行组织病理学检查。收集患者年龄、性别、病变部位、肿瘤切除范围及复发情况等数据。采用描述性和推断性统计方法描述研究亚组。
共851例眼睑肿瘤纳入研究样本。其中恶性病例351例(41.2%),良性病例500例(58.8%)。恶性肿瘤中,基底细胞癌占86%,鳞状细胞癌占7%,基底鳞状细胞癌占7%。良性眼睑病变中,囊肿占20%,脂溢性角化病占18%,痣占13%,乳头状瘤占13%。良性眼睑病变在上睑和下睑的发生率相同。恶性病变更常见于下睑。良性病变患者的诊断平均年龄为49±1.45岁,恶性病变患者为67±1.6岁。
在这个希腊队列中,良性眼睑病变主要影响年轻人,恶性病变主要发生在老年患者中。男性和女性受恶性病变的影响相同,手术切除后复发罕见。