Samiul Islam Md, Parvin Sultana, Mahbubur Rahman Khan Mohammad, Jahangir Hossain G M, Zahiruddin A K M, Jahangir Alam Md, Hossen Monaim, Wahidur Rahman Md, Shahidul Islam Syed, Abdul Gani Mollah Md
National Institute of Traumatology & Orthopedic Rehabilitation, (NITOR) Dhaka-1207, Bangladesh.
Sheikh Russel National Gastroliver Institute & Hospital. Mohakhali, Dhaka 1212, Bangladesh.
Clin Infect Pract. 2022 Jan;13:100131. doi: 10.1016/j.clinpr.2021.100131. Epub 2022 Jan 3.
Asymptomatic COVID-19 patients are the most challenging and feared obstacles in resuming these surgical procedures. The purpose of this study was to evaluate the proportion of asymptomatic carriers detected by RT-PCR in pre-operative orthopaedic evaluation during the peak of the second wave.
514 asymptomtomatic COVID-19 patients, negative for TOCC (Travel, Profession, Cluster, Contact) risk factors were observed retrospectively. A nasopharyFngeal RT-PCR test was obtained 48 to 72 h before the surgery in all cases. Possible risk factors for a positive test was identified.
The detected asymptomatic COVID-19 infection rate during the peak of the second wave among the pre-operative orthopaedic patients was 12.3%. Younger age, female gender, longer duration of admission to RT-PCR test interval were found to be significant (p= < 0.05) risk factors for asymptomatic RT-PCR to be positive. The hazard ratio (HR) for being asymptomatic RT-PCR positive was 4.3 (p = 0. 025), while the RT-PCR was performed at 14 days, but the HR increased to 9.2 (p = 0.049) when the test was performed after 45 days.
According to our findings, pre-operative testing to rule out COVID-19 should be regarded as a critical step in preventing the disease clusters in hospitals.
无症状的新冠病毒肺炎患者是恢复这些外科手术过程中最具挑战性且令人担忧的障碍。本研究的目的是评估在第二波疫情高峰期，术前骨科评估中通过逆转录聚合酶链反应（RT-PCR）检测出的无症状携带者的比例。
回顾性观察514例无症状新冠病毒肺炎患者，这些患者不存在旅行、职业、聚集性感染、接触等（TOCC）风险因素。所有病例均在手术前48至72小时进行了鼻咽部RT-PCR检测。确定了检测结果呈阳性的可能风险因素。
在第二波疫情高峰期，术前骨科患者中检测到的无症状新冠病毒肺炎感染率为12.3%。年龄较小、女性、从入院到RT-PCR检测的间隔时间较长被发现是无症状RT-PCR检测呈阳性的显著（p = < 0.05）风险因素。无症状RT-PCR检测呈阳性的风险比（HR）为4.3（p = 0.025），而RT-PCR检测在14天时进行，但当检测在45天后进行时，HR增加到9.2（p = 0.049）。
根据我们的研究结果，术前检测以排除新冠病毒肺炎应被视为预防医院内疾病聚集的关键步骤。
