Moule S K, McGivan J D
Department of Biochemistry, University of Bristol Medical School, U.K.
Biochem J. 1987 Oct 1;247(1):233-5. doi: 10.1042/bj2470233.
Epidermal growth factor causes a transient stimulation of alanine transport in hepatocytes. The stimulation is maximal after 30 min, and the rate returns to the control value after 90 min. These characteristics are very similar to the short-term stimulation of alanine transport by glucagon, which has been attributed to cell membrane hyperpolarization.
表皮生长因子可引起肝细胞中丙氨酸转运的短暂刺激。这种刺激在30分钟后达到最大值,90分钟后速率恢复到对照值。这些特征与胰高血糖素对丙氨酸转运的短期刺激非常相似,后者被认为是由于细胞膜超极化所致。