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表皮生长因子与胰高血糖素一样,对大鼠肝细胞中的丙氨酸转运具有短期刺激作用。

Epidermal growth factor, like glucagon, exerts a short-term stimulation of alanine transport in rat hepatocytes.

作者信息

Moule S K, McGivan J D

机构信息

Department of Biochemistry, University of Bristol Medical School, U.K.

出版信息

Biochem J. 1987 Oct 1;247(1):233-5. doi: 10.1042/bj2470233.

Abstract

Epidermal growth factor causes a transient stimulation of alanine transport in hepatocytes. The stimulation is maximal after 30 min, and the rate returns to the control value after 90 min. These characteristics are very similar to the short-term stimulation of alanine transport by glucagon, which has been attributed to cell membrane hyperpolarization.

摘要

表皮生长因子可引起肝细胞中丙氨酸转运的短暂刺激。这种刺激在30分钟后达到最大值,90分钟后速率恢复到对照值。这些特征与胰高血糖素对丙氨酸转运的短期刺激非常相似,后者被认为是由于细胞膜超极化所致。

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