School of Environment and Energy, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou, China.
The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou, China.
PLoS One. 2022 Jan 10;17(1):e0261306. doi: 10.1371/journal.pone.0261306. eCollection 2022.
The effect of tetracycline (TC) on nitrogen removal in wastewater treatment plants has become a new problem. This study investigated the effects of TC on nitrogen removal using a Moving Bed Biofilm Reactor system. The results showed that there was no significant effect on nitrogen removal performance when the concentration of TC was 5 mg/L, and that the total nitrogen (TN) removal efficiency could reach 75-77%. However, when the concentration of TC increased to 10 mg/L, the denitrification performance was affected and the TN removal efficiency decreased to 58%. The abundance of denitrifying bacteria such as those in the genus Thauera decreased, and TC-resistant bacteria gradually became dominant. At a TC concentration of 10 mg/L, there were also increases and decreases, respectively, in the abundance of resistance and denitrification functional genes. The inhibitory effect of TC on denitrification was achieved mainly by the inhibition of nitrite-reducing bacteria.
四环素（TC）对污水处理厂脱氮的影响已成为一个新问题。本研究采用移动床生物膜反应器系统，考察了 TC 对氮去除的影响。结果表明，当 TC 浓度为 5mg/L 时，对氮去除性能无明显影响，总氮（TN）去除率可达 75-77%。然而，当 TC 浓度增加到 10mg/L 时，反硝化性能受到影响，TN 去除效率下降至 58%。反硝化菌如 Thauera 属的丰度减少，而 TC 抗性菌逐渐占据优势。在 TC 浓度为 10mg/L 时，抗性和反硝化功能基因的丰度也分别增加和减少。TC 对反硝化的抑制作用主要是通过抑制亚硝酸盐还原菌来实现的。
