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葡萄膜炎的脉络膜成像:更新。

Choroidal imaging in uveitis: An update.

机构信息

Uveitis Services, Neoretina Eyecare Institute, Hyderabad, India.

Department of Ophthalmology, Department of Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

出版信息

Surv Ophthalmol. 2022 Jul-Aug;67(4):965-990. doi: 10.1016/j.survophthal.2022.01.001. Epub 2022 Jan 7.

DOI:10.1016/j.survophthal.2022.01.001
PMID:35007618
Abstract

An important goal of advancements in ocular imaging algorithms and devices has been to improve the image acquisition and resolution of deeper ocular tissues, namely the choroid and its vasculature that are otherwise inaccessible to direct clinical examination. These advancements have contributed to the understanding of the pathophysiology of a number of ocular inflammatory conditions. We focus on the imaging characteristics of clinical conditions where imaging the choroid has improved or radically changed the understanding of the disease, has helped in differentiation of phenotypically similar but distinct lesions, and where imaging features have proven vital for monitoring disease activity. The last two decades have seen some major developments in ocular imaging relevant to uveitis. The current review addresses both the imaging characteristics and their interpretation on conventional modalities such as fundus photography, fluorescein angiography, indocyanine green angiography, and fundus autofluorescence and the recent additions in the armamentarium including optical coherence tomography (OCT) with enhanced depth imaging, swept-source OCT, and OCT angiography.

摘要

眼部成像算法和设备的重要进展目标之一是提高深层眼部组织(即脉络膜及其脉管系统)的图像采集和分辨率,这些组织通常无法进行直接的临床检查。这些进展有助于了解许多眼部炎症性疾病的病理生理学。我们重点介绍了那些通过成像脉络膜改善或彻底改变了对疾病的理解、有助于区分表型相似但不同病变、以及成像特征对监测疾病活动至关重要的临床情况的成像特征。过去二十年中,与葡萄膜炎相关的眼部成像有了一些重大进展。本综述既介绍了传统成像方式(如眼底摄影、荧光素血管造影、吲哚青绿血管造影和眼底自发荧光)的成像特征及其解释,也介绍了包括增强深度成像的光学相干断层扫描(OCT)、扫频源 OCT 和 OCT 血管造影等新工具的应用。

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