Guo S, Yang P Z
Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing 400016, China.
Zhonghua Yan Ke Za Zhi. 2023 Aug 11;59(8):677-681. doi: 10.3760/cma.j.cn112142-20220905-00433.
Non-infectious uveitis (NIU) is a challenging type of intraocular inflammatory disease that tends to recur and can be resistant to treatment. It can cause both transient and permanent pathological changes in the retina and choroid. Accurate diagnosis and monitoring of these changes rely heavily on ophthalmic imaging methods. In recent years, the enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT), swept-source optical coherence tomography (SS-OCT), and swept-source optical coherence tomography angiography (SS-OCTA) have emerged as rapidly evolving ophthalmic imaging techniques that offer significant advantages in evaluating choroidal thickness, displaying the whole choroid, and monitoring choroidal blood flow. This review provides an overview of the current research status of EDI-OCT, SS-OCT, and SS-OCTA in evaluating intraocular inflammation and other choroid-related complications in noninfectious intermediate uveitis, posterior uveitis, and panuveitis, and also highlights their future prospects.
非感染性葡萄膜炎(NIU)是一种具有挑战性的眼内炎性疾病,容易复发且可能对治疗产生耐药性。它可导致视网膜和脉络膜出现短暂和永久性的病理变化。对这些变化的准确诊断和监测在很大程度上依赖于眼科成像方法。近年来,增强深度成像光谱域光学相干断层扫描(EDI-OCT)、扫频光学相干断层扫描(SS-OCT)和扫频光学相干断层扫描血管造影(SS-OCTA)已成为快速发展的眼科成像技术,在评估脉络膜厚度、显示整个脉络膜以及监测脉络膜血流方面具有显著优势。本文综述了EDI-OCT、SS-OCT和SS-OCTA在评估非感染性中间葡萄膜炎、后葡萄膜炎和全葡萄膜炎的眼内炎症及其他脉络膜相关并发症方面的研究现状,并对其未来前景进行了展望。