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新型冠状病毒肺炎对男性生育力的影响。

Impact of COVID-19 on Male Fertility.

机构信息

Department of Microbiology, Immunology & Pathology, Des Moines University College of Osteopathic Medicine, Des Moines, IA.

Department of Respiratory Medicine, the 2nd People's Hospital of Hefei and Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.

出版信息

Urology. 2022 Jun;164:33-39. doi: 10.1016/j.urology.2021.12.025. Epub 2022 Jan 8.

DOI:10.1016/j.urology.2021.12.025
PMID:35007621
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8741337/
Abstract

COVID-19, the clinical condition caused by the SARS-CoV-2 virus, has been associated with massive cytokine storm and damage to multiple organ systems. Although evidence for the detection of SARS-CoV-2 virus in the testis remains scarce, testicular damage and dysregulation of gonadotropins associated with inflammation has been reported. Additionally, as a result of the rapidly evolving pandemic, frequently updated medical interventions and public policies leading to delays of care can play a role in fertility. This narrative review aims to summarize the current literature on how COVID-19 may influence male fertility.

摘要

新型冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)引起的临床疾病,与大量细胞因子风暴和多器官系统损伤有关。尽管在睾丸中检测到 SARS-CoV-2 病毒的证据仍然很少,但已有报道称与炎症相关的睾丸损伤和促性腺激素失调。此外,由于大流行迅速演变,经常更新的医疗干预措施和公共政策导致延迟治疗,可能会对生育能力产生影响。本综述旨在总结目前关于 COVID-19 如何影响男性生育力的文献。

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本文引用的文献

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Cell J. 2021 Sep;23(4):382-388. doi: 10.22074/cellj.2021.7982. Epub 2021 Aug 29.
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Andrologia. 2021 Oct;53(9):e14157. doi: 10.1111/and.14157. Epub 2021 Jul 15.
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Sperm Parameters Before and After COVID-19 mRNA Vaccination.新冠肺炎 mRNA 疫苗接种前后的精子参数。
JAMA. 2021 Jul 20;326(3):273-274. doi: 10.1001/jama.2021.9976.
4
COVID-19 disrupts spermatogenesis through the oxidative stress pathway following induction of apoptosis.COVID-19 通过诱导细胞凋亡,经氧化应激途径破坏精子发生。
Apoptosis. 2021 Aug;26(7-8):415-430. doi: 10.1007/s10495-021-01680-2. Epub 2021 Jun 2.
5
Evaluation of SARS-CoV-2 in Human Semen and Effect on Total Sperm Number: A Prospective Observational Study.人类精液中新型冠状病毒 2 型的评估及其对精子总数的影响:一项前瞻性观察研究。
World J Mens Health. 2021 Jul;39(3):489-495. doi: 10.5534/wjmh.200192. Epub 2021 Feb 24.
6
The Johnson & Johnson Vaccine for COVID-19.强生公司的新冠疫苗。
JAMA. 2021 Apr 20;325(15):1575. doi: 10.1001/jama.2021.2927.
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Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1663-1669. doi: 10.26355/eurrev_202102_24877.
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