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基质效应物与癌症

Matrix Effectors and Cancer.

作者信息

Piperigkou Zoi, Karamanos Nikos K

机构信息

Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 265 04 Patras, Greece.

Foundation for Research and Technology-Hellas (FORTH)/Institute of Chemical Engineering Sciences (ICE-HT), 265 04 Patras, Greece.

出版信息

Cancers (Basel). 2021 Dec 31;14(1):200. doi: 10.3390/cancers14010200.

Abstract

Extracellular matrices (ECMs) are highly dynamic three-dimensional structural meshworks composed of macromolecules, such as proteoglycans/glycosaminoglycans (PGs/GAGs), collagens, laminins, elastin, (glyco)proteins, and matrix-degrading enzymes, such as proteases and glycosidases [...].

摘要

细胞外基质(ECMs)是由大分子组成的高度动态的三维结构网络,这些大分子包括蛋白聚糖/糖胺聚糖(PGs/GAGs)、胶原蛋白、层粘连蛋白、弹性蛋白、(糖)蛋白,以及基质降解酶,如蛋白酶和糖苷酶[……]

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