• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于堆叠式激光微点焊(JS-LMSW)制造的用于组织工程应用的多孔支架的表征

Characterization of Porous Scaffolds Fabricated by Joining Stacking Based Laser Micro-Spot Welding (JS-LMSW) for Tissue Engineering Applications.

作者信息

Cedeño-Viveros Luis D, Rodriguez Ciro A, Segura-Ibarra Victor, Vázquez Elisa, García-López Erika

机构信息

Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Ave. Eugenio Garza Sada 2501, Monterrey 64849, Mexico.

Laboratorio Nacional de Manufactura Aditiva y Digital (MADiT), Apodaca 66629, Mexico.

出版信息

Materials (Basel). 2021 Dec 23;15(1):99. doi: 10.3390/ma15010099.

DOI:10.3390/ma15010099
PMID:35009246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8745960/
Abstract

A novel manufacturing approach was used to fabricate metallic scaffolds. A calibration of the laser cutting process was performed using the kerf width compensation in the calculations of the tool trajectory. Welding defects were studied through X-ray microtomography. Penetration depth and width resulted in relative errors of 9.4%, 1.0%, respectively. Microhardness was also measured, and the microstructure was studied in the base material. The microhardness values obtained were 400 HV, 237 HV, and 215 HV for the base material, HAZ, and fusion zone, respectively. No significant difference was found between the microhardness measurement along with different height positions of the scaffold. The scaffolds' dimensions and porosity were measured, their internal architecture was observed with micro-computed tomography. The results indicated that geometries with dimensions under 500 µm with different shapes resulted in relative errors of ~2.7%. The fabricated scaffolds presented an average compressive modulus ~13.15 GPa, which is close to cortical bone properties. The proposed methodology showed a promising future in bone tissue engineering applications.

摘要

采用一种新型制造方法来制造金属支架。在刀具轨迹计算中使用切口宽度补偿对激光切割工艺进行校准。通过X射线显微断层扫描研究焊接缺陷。熔深和熔宽的相对误差分别为9.4%和1.0%。还测量了显微硬度,并研究了母材的微观结构。母材、热影响区和熔合区获得的显微硬度值分别为400 HV、237 HV和215 HV。在支架不同高度位置进行的显微硬度测量之间未发现显著差异。测量了支架的尺寸和孔隙率,用微型计算机断层扫描观察其内部结构。结果表明,尺寸小于500 µm且形状不同的几何形状导致的相对误差约为2.7%。制造的支架呈现出平均压缩模量约为13.15 GPa,这与皮质骨特性相近。所提出的方法在骨组织工程应用中显示出有前景的未来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/8f809a918bf5/materials-15-00099-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/f9ef71ecb8ca/materials-15-00099-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/c4b7992b4cb9/materials-15-00099-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/61e93bf6ce59/materials-15-00099-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/6556f98219e1/materials-15-00099-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/aab78219d20c/materials-15-00099-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/aa0f6d09c4c5/materials-15-00099-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/ad9e7c07754b/materials-15-00099-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/a0873475f28e/materials-15-00099-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/8b8e5d823022/materials-15-00099-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/069d37c7a4b3/materials-15-00099-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/ccfee1ce413e/materials-15-00099-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/5621e83aae11/materials-15-00099-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/53569ccf84c9/materials-15-00099-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/08d2476d1c6c/materials-15-00099-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/8f809a918bf5/materials-15-00099-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/f9ef71ecb8ca/materials-15-00099-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/c4b7992b4cb9/materials-15-00099-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/61e93bf6ce59/materials-15-00099-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/6556f98219e1/materials-15-00099-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/aab78219d20c/materials-15-00099-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/aa0f6d09c4c5/materials-15-00099-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/ad9e7c07754b/materials-15-00099-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/a0873475f28e/materials-15-00099-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/8b8e5d823022/materials-15-00099-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/069d37c7a4b3/materials-15-00099-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/ccfee1ce413e/materials-15-00099-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/5621e83aae11/materials-15-00099-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/53569ccf84c9/materials-15-00099-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/08d2476d1c6c/materials-15-00099-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a12/8745960/8f809a918bf5/materials-15-00099-g015.jpg

相似文献

1
Characterization of Porous Scaffolds Fabricated by Joining Stacking Based Laser Micro-Spot Welding (JS-LMSW) for Tissue Engineering Applications.基于堆叠式激光微点焊(JS-LMSW)制造的用于组织工程应用的多孔支架的表征
Materials (Basel). 2021 Dec 23;15(1):99. doi: 10.3390/ma15010099.
2
Fatigue behavior of As-built selective laser melted titanium scaffolds with sheet-based gyroid microarchitecture for bone tissue engineering.基于片层双曲蜂巢结构的增材制造钛支架疲劳行为及其在骨组织工程中的应用
Acta Biomater. 2019 Aug;94:610-626. doi: 10.1016/j.actbio.2019.05.046. Epub 2019 May 22.
3
Microstructure and compression properties of 3D powder printed Ti-6Al-4V scaffolds with designed porosity: Experimental and computational analysis.具有设计孔隙率的3D粉末打印Ti-6Al-4V支架的微观结构和压缩性能:实验与计算分析
Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 1):812-823. doi: 10.1016/j.msec.2016.09.040. Epub 2016 Sep 21.
4
Additive manufacturing of hydroxyapatite-chitosan-genipin composite scaffolds for bone tissue engineering applications.用于骨组织工程应用的羟基磷灰石-壳聚糖-京尼平复合支架的增材制造。
Mater Sci Eng C Mater Biol Appl. 2021 Feb;119:111639. doi: 10.1016/j.msec.2020.111639. Epub 2020 Oct 17.
5
Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering.使用通过选择性激光烧结制造的聚己内酯支架进行骨组织工程。
Biomaterials. 2005 Aug;26(23):4817-27. doi: 10.1016/j.biomaterials.2004.11.057. Epub 2005 Jan 23.
6
Micromechanical finite-element modeling and experimental characterization of the compressive mechanical properties of polycaprolactone-hydroxyapatite composite scaffolds prepared by selective laser sintering for bone tissue engineering.采用选择性激光烧结技术制备用于骨组织工程的聚己内酯-羟基磷灰石复合支架的压缩力学性能的微机械有限元建模与实验表征。
Acta Biomater. 2012 Aug;8(8):3138-43. doi: 10.1016/j.actbio.2012.04.022. Epub 2012 Apr 19.
7
Customized additive manufacturing of porous Ti6Al4V scaffold with micro-topological structures to regulate cell behavior in bone tissue engineering.定制具有微观拓扑结构的多孔 Ti6Al4V 支架的增材制造以调节骨组织工程中的细胞行为。
Mater Sci Eng C Mater Biol Appl. 2021 Jan;120:111789. doi: 10.1016/j.msec.2020.111789. Epub 2020 Dec 10.
8
Preparation and characterization of PLA/PCL/HA composite scaffolds using indirect 3D printing for bone tissue engineering.采用间接 3D 打印技术制备 PLA/PCL/HA 复合支架用于骨组织工程。
Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109960. doi: 10.1016/j.msec.2019.109960. Epub 2019 Jul 6.
9
Permeability and mechanical properties of gradient porous PDMS scaffolds fabricated by 3D-printed sacrificial templates designed with minimal surfaces.采用最小曲面设计的 3D 打印牺牲模板制备的梯度多孔 PDMS 支架的渗透性和机械性能。
Acta Biomater. 2019 Sep 15;96:149-160. doi: 10.1016/j.actbio.2019.06.040. Epub 2019 Jun 25.
10
Selective laser sintered bio-inspired silicon-wollastonite scaffolds for bone tissue engineering.用于骨组织工程的选择性激光烧结生物启发式硅灰石支架
Mater Sci Eng C Mater Biol Appl. 2020 Nov;116:111223. doi: 10.1016/j.msec.2020.111223. Epub 2020 Jun 20.

本文引用的文献

1
Additive Manufacturing of Material Scaffolds for Bone Regeneration: Toward Application in the Clinics.用于骨再生的材料支架的增材制造:迈向临床应用
Adv Funct Mater. 2020 Oct 15;31(5). doi: 10.1002/adfm.202006967. eCollection 2021 Jan 27.
2
The rationale behind implant coatings to promote osteointegration, bone healing or regeneration.种植体涂层促进骨整合、骨愈合或再生的原理。
Injury. 2021 Jun;52 Suppl 2:S106-S111. doi: 10.1016/j.injury.2020.11.050. Epub 2020 Nov 21.
3
Challenges on optimization of 3D-printed bone scaffolds.
3D 打印骨支架优化面临的挑战。
Biomed Eng Online. 2020 Sep 3;19(1):69. doi: 10.1186/s12938-020-00810-2.
4
Recent Developments of Biomaterials for Additive Manufacturing of Bone Scaffolds.用于骨支架增材制造的生物材料的最新进展
Adv Healthc Mater. 2020 Dec;9(23):e2000724. doi: 10.1002/adhm.202000724. Epub 2020 Aug 2.
5
Influence of the Elastic Modulus on the Osseointegration of Dental Implants.弹性模量对牙种植体骨结合的影响。
Materials (Basel). 2019 Mar 25;12(6):980. doi: 10.3390/ma12060980.
6
Fabrication of Scaffolds for Bone-Tissue Regeneration.用于骨组织再生的支架的制造。
Materials (Basel). 2019 Feb 14;12(4):568. doi: 10.3390/ma12040568.
7
Bone Mechanical Properties in Healthy and Diseased States.健康与患病状态下的骨骼力学特性
Annu Rev Biomed Eng. 2018 Jun 4;20:119-143. doi: 10.1146/annurev-bioeng-062117-121139.
8
Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep.机械生物学优化的 3D 钛网支架增强绵羊临界节段性缺损中的骨再生。
Sci Transl Med. 2018 Jan 10;10(423). doi: 10.1126/scitranslmed.aam8828.
9
Metallic powder-bed based 3D printing of cellular scaffolds for orthopaedic implants: A state-of-the-art review on manufacturing, topological design, mechanical properties and biocompatibility.用于骨科植入物的基于金属粉末床的细胞支架3D打印:关于制造、拓扑设计、力学性能和生物相容性的最新综述
Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:1328-1343. doi: 10.1016/j.msec.2017.02.094. Epub 2017 Feb 24.
10
Biomechanical Consequences of the Elastic Properties of Dental Implant Alloys on the Supporting Bone: Finite Element Analysis.牙种植体合金弹性特性对支持骨的生物力学影响:有限元分析
Biomed Res Int. 2016;2016:1850401. doi: 10.1155/2016/1850401. Epub 2016 Nov 22.