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南非豪登省和西北省金矿尾矿堆附近青少年的过敏和家庭生活条件。

Allergy and Household Living Conditions among Adolescents Living near Gold Mine Tailing Dumps in the Gauteng and North West Provinces of South Africa.

机构信息

School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.

Environment and Health Research Unit, South African Medical Research Council, Johannesburg 2094, South Africa.

出版信息

Int J Environ Res Public Health. 2021 Dec 23;19(1):122. doi: 10.3390/ijerph19010122.

Abstract

This quantitative exploratory baseline study aimed to investigate whether allergy among adolescents was associated with household living conditions, including living near gold mine tailing dumps in South Africa. A questionnaire based on the International Study of Asthma and Allergies was used to collect information on allergy and household risk factors among adolescents ( = 5611). A chi-square test was applied to determine the relationship between community (exposed/unexposed) and confounding variables. Crude and adjusted odds ratios (ORs) and 95% confidence intervals (CI) were calculated using univariate and multiple logistic regression analysis (LRA) to estimate the likelihood of having doctor-diagnosed allergies. The overall prevalence of doctor-diagnosed allergies was 25.5%. The exposed communities had a higher prevalence of doctor-diagnosed allergies (26.97%) compared with the unexposed (22.69%) communities. The study found an association between doctor-diagnosed allergy and having fungus in the house, being female, currently having pets in and around the house, residing in the community for more than three years and living in communities located close to gold mine tailing dumps. Actions to implement buffer zones between gold mine tailing dumps and communities would support Sustainable Development Goals 3 (health) and 11 (sustainable cities and communities), while failing to address the current potential identified risk factors may pose a significant public health challenge. Local policymakers should also apply the precautionary principle to protect the health of children, especially with the location of human settlements relative to air pollution sources.

摘要

这项定量探索性基线研究旨在调查青少年过敏是否与家庭生活条件有关,包括居住在南非金矿尾矿堆附近的情况。研究采用基于国际哮喘和过敏研究的问卷,收集了青少年过敏和家庭危险因素的信息(n=5611)。应用卡方检验来确定社区(暴露/非暴露)与混杂变量之间的关系。使用单变量和多因素逻辑回归分析(LRA)计算粗比值比(OR)和 95%置信区间(CI),以评估患有医生诊断的过敏的可能性。医生诊断的过敏总患病率为 25.5%。暴露社区的医生诊断的过敏患病率(26.97%)高于非暴露社区(22.69%)。研究发现,医生诊断的过敏与家中有真菌、女性、家中目前有宠物、在社区居住超过三年以及居住在靠近金矿尾矿堆的社区有关。在金矿尾矿堆和社区之间实施缓冲区的行动将支持可持续发展目标 3(健康)和 11(可持续城市和社区),而未能解决当前潜在的风险因素可能会对公共健康构成重大挑战。地方政策制定者还应运用预防原则来保护儿童的健康,特别是考虑到人类住区相对于空气污染来源的位置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c6b/8750766/4dfaa1b9d542/ijerph-19-00122-g001.jpg

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