1st Propaedeutic Department of Internal Medicine, Medical School, University General Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
1st Propaedeutic Surgical Department, University Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki (AUTH), 54636 Thessaloniki, Greece.
Nutrients. 2021 Dec 31;14(1):192. doi: 10.3390/nu14010192.
Diabetes mellitus has been steadily increasing over the past decades and is one of the most significant global public health concerns. Diabetes mellitus patients have an increased risk of both surgical and post-surgical complications. The post-surgical risks are associated with the primary condition that led to surgery and the hyperglycaemia per se. Gut microbiota seems to contribute to glucose homeostasis and insulin resistance. It affects the metabolism through body weight and energy homeostasis, integrating the peripheral and central food intake regulatory signals. Homeostasis of gut microbiota seems to be enhanced by probiotics pre and postoperatively. The term probiotics is used to describe some species of live microorganisms that, when administered in adequate amounts, confer health benefits on the host. The role of probiotics in intestinal or microbial skin balance after abdominal or soft tissue elective surgeries on DM patients seems beneficial, as it promotes anti-inflammatory cytokine production while increasing the wound-healing process. This review article aims to present the interrelation of probiotic supplements with DM patients undergoing elective surgeries.
在过去几十年中，糖尿病的发病率一直在稳步上升，是全球最重要的公共卫生问题之一。糖尿病患者在手术中和手术后都有更高的并发症风险。这些术后风险与导致手术的基础疾病以及高血糖本身有关。肠道微生物群似乎有助于葡萄糖的体内平衡和胰岛素抵抗。它通过体重和能量的体内平衡来影响代谢，整合外周和中枢的食物摄入调节信号。术前和术后使用益生菌可以增强肠道微生物群的体内平衡。益生菌这个术语用于描述一些种类的活微生物，当以足够的量使用时，可以为宿主带来健康益处。益生菌在 DM 患者接受腹部或软组织择期手术后的肠道或微生物皮肤平衡中的作用似乎是有益的，因为它可以促进抗炎细胞因子的产生，同时加速伤口愈合过程。这篇综述文章旨在介绍益生菌补充剂与接受择期手术的糖尿病患者之间的相互关系。
