Imamura Teruhiko, Gonoi Wataru, Hori Masakazu, Ueno Yohei, Narang Nikhil, Onoda Hiroshi, Tanaka Shuhei, Nakamura Makiko, Kataoka Naoya, Ushijima Ryuichi, Sobajima Mitsuo, Fukuda Nobuyuki, Ueno Hiroshi, Kinugawa Koichiro
Second Department of Internal Medicine, University of Toyama, Toyama 9300194, Japan.
Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo 1138654, Japan.
J Clin Med. 2021 Dec 29;11(1):164. doi: 10.3390/jcm11010164.
The accuracy of the remote dielectric sensing (ReDS) system, which is a noninvasive electromagnetic-based technology to quantify lung fluid levels, particularly among those with small body size, remains uncertain.
Hospitalized patients with and without heart failure underwent assessment of lung fluid levels with ReDS and successive chest computed tomography imaging. We performed a correlation analysis of the ReDS measurement, representing lung fluid levels, and computed tomography-derived high attenuation area percentage, which also provides a spatial quantification of lung fluid level.
A total of 46 patients (median 76 years old, 28 men), including 28 patients with heart failure, were included. The median ReDS value was 28% (interquartile: 23%, 33%), and the median percentage of high attenuation area was 21.6% (14.4%, 28.5%). ReDS values and percentage of high attenuation area were moderately correlated (r = 0.65, < 0.001), irrespective of the existence of heart failure. ReDS value independently predicted the percentage of high attenuation area seen on computed tomography ( < 0.001).
The ReDS system may be a promising, noninvasive tool to quantify fluid lung levels, as validated by comparison with chest computed tomography imaging. Further studies are warranted to validate the utility and applicability of this technology to a variety of clinical scenarios.
远程介电传感（ReDS）系统是一种基于非侵入性电磁技术来量化肺内液体水平的方法，其准确性，尤其是在体型较小的人群中，仍不确定。
对住院的有和没有心力衰竭的患者进行了ReDS肺内液体水平评估以及连续的胸部计算机断层扫描成像。我们对代表肺内液体水平的ReDS测量值与计算机断层扫描得出的高衰减面积百分比进行了相关性分析，后者也提供了肺内液体水平的空间量化。
共纳入46例患者（中位年龄76岁，28例男性），其中包括28例心力衰竭患者。ReDS值中位数为28%（四分位间距：23%，33%），高衰减面积百分比中位数为21.6%（14.4%，28.5%）。无论是否存在心力衰竭，ReDS值与高衰减面积百分比均呈中度相关（r = 0.65，<0.001）。ReDS值可独立预测计算机断层扫描上所见的高衰减面积百分比（<0.001）。
通过与胸部计算机断层扫描成像比较验证，ReDS系统可能是一种很有前景的非侵入性量化肺内液体水平的工具。有必要进行进一步研究以验证该技术在各种临床场景中的实用性和适用性。
