Wei Sixuan, Peng Rujie, Bian Shilong, Han Wei, Xiao Biao, Peng Xianghong
Key Laboratory of Optoelectronic Chemical Materials and Devices (Ministry of Education), School of Optoelectronic Materials & Technology, Jianghan University, Wuhan 430056, China.
Polymers (Basel). 2021 Dec 25;14(1):69. doi: 10.3390/polym14010069.
Chitosan-based nanostructures have been widely applied in biomineralization and biosensors owing to its polycationic properties. The creation of chitosan nanostructures with controllable morphology is highly desirable, but has met with limited success yet. Here, we report that nanostructured chitosan tartaric sodium (CS-TA-Na) is simply synthesized in large amounts from chitosan tartaric ester (CS-TA) hydrolyzed by NaOH solution, while the CS-TA is obtained by dehydration-caused crystallization. The structures and self-assembly properties of CS-TA-Na are carefully characterized by Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy (H-NMR), X-ray diffraction (XRD), differential scanning calorimeter (DSC), transmission electron microscopy (TEM), a scanning electron microscope (SEM) and a polarizing optical microscope (POM). As a result, the acquired nanostructured CS-TA-Na, which is dispersed in an aqueous solution 20-50 nm in length and 10-15 nm in width, shows both the features of carboxyl and amino functional groups. Moreover, morphology regulation of the CS-TA-Na nanostructures can be easily achieved by adjusting the solvent evaporation temperature. When the evaporation temperature is increased from 4 °C to 60 °C, CS-TA-Na nanorods and nanosheets are obtained on the substrates, respectively. As far as we know, this is the first report on using a simple solvent evaporation method to prepare CS-TA-Na nanocrystals with controllable morphologies.
基于壳聚糖的纳米结构因其聚阳离子特性已被广泛应用于生物矿化和生物传感器领域。制备具有可控形态的壳聚糖纳米结构是非常必要的，但目前取得的成功有限。在此，我们报告通过用氢氧化钠溶液水解壳聚糖酒石酸酯（CS-TA）可大量简单合成纳米结构的壳聚糖酒石酸钠（CS-TA-Na），而CS-TA是通过脱水结晶获得的。通过傅里叶变换红外光谱（FTIR）、核磁共振光谱（H-NMR）、X射线衍射（XRD）、差示扫描量热仪（DSC）、透射电子显微镜（TEM）、扫描电子显微镜（SEM）和偏光光学显微镜（POM）对CS-TA-Na的结构和自组装性质进行了仔细表征。结果表明，所获得的纳米结构CS-TA-Na分散在水溶液中，长度为20 - 50 nm，宽度为10 - 15 nm，同时具有羧基和氨基官能团的特征。此外，通过调节溶剂蒸发温度可以轻松实现CS-TA-Na纳米结构的形态调控。当蒸发温度从4℃升高到60℃时，分别在基底上获得了CS-TA-Na纳米棒和纳米片。据我们所知，这是首次报道使用简单的溶剂蒸发方法制备具有可控形态的CS-TA-Na纳米晶体。
