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本文引用的文献

1
Growth factor regulatory system: a new system for not truly recognized organisms.生长因子调节系统:一种针对未被充分认识的生物体的新系统。
Sci China Life Sci. 2020 Mar;63(3):443-446. doi: 10.1007/s11427-019-1590-x. Epub 2020 Jan 13.
2
Looking east.向东看。
Int J Low Extrem Wounds. 2012 Sep;11(3):146. doi: 10.1177/1534734612456921.
3
Adult stem cells for tissue repair - a new therapeutic concept?用于组织修复的成体干细胞——一种新的治疗理念?
N Engl J Med. 2003 Aug 7;349(6):570-82. doi: 10.1056/NEJMra022361.
4
Recombinant bovine basic fibroblast growth factor accelerates wound healing in patients with burns, donor sites and chronic dermal ulcers.重组牛碱性成纤维细胞生长因子可加速烧伤、供皮区及慢性皮肤溃疡患者的伤口愈合。
Chin Med J (Engl). 2000 Apr;113(4):367-71.
5
Dedifferentiation of epidermal cells to stem cells in vivo.
Lancet. 2001 Sep 29;358(9287):1067-8. doi: 10.1016/S0140-6736(01)06202-X.
6
Bridging traditions.融合传统。
Wound Repair Regen. 2001 Jan-Feb;9(1):1. doi: 10.1046/j.1524-475x.2001.00001.x.
7
Randomised placebo-controlled trial of use of topical recombinant bovine basic fibroblast growth factor for second-degree burns.外用重组牛碱性成纤维细胞生长因子治疗二度烧伤的随机安慰剂对照试验
Lancet. 1998 Nov 21;352(9141):1661-4. doi: 10.1016/S0140-6736(98)01260-4.

基于工程化生长因子研究与应用建立创伤与烧伤治疗的“中国模式”

[Establishment of "Chinese way" for trauma and burn management based on the engineered growth factors research and application].

作者信息

Fu X B, Li X K

机构信息

Research Center for Wound Repair and Tissue Regeneration, Medical Innovation Research Department, the PLA General Hospital, Beijing 100853, China The Key Laboratory of PLA Wound Repair and Tissue Regeneration, the Fourth Medical Center of PLA General Hospital, Beijing 100048, China.

School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jan 20;38(1):4-8. doi: 10.3760/cma.j.cn501120-20211125-00397.

DOI:10.3760/cma.j.cn501120-20211125-00397
PMID:35012265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11705269/
Abstract

Innovation and translation application are important topics that have been discussed repeatedly in national community of science and technology in recent years. We do a systemic review about the research and development history of growth factors, their application in trauma and burn management in China, and the conception and experience about the establishment of "Chinese way" for trauma and burn management in the process of constructing a disciplinary system for wound treatment with Chinese characteristics. It is our hope that these precious experiences will provide references and inspiration to our peers, especially the young generation in their research.

摘要

创新与转化应用是近年来国家科技界反复探讨的重要话题。我们对生长因子的研发历程、其在中国创伤与烧伤治疗中的应用,以及在构建具有中国特色的创面治疗学科体系过程中关于创伤与烧伤治疗“中国道路”建立的理念与经验进行了系统综述。希望这些宝贵经验能为同行,尤其是年轻一代的研究提供参考与启示。