Hajiioannou J, Gkrinia E, Tzimkas-Dakis K, Palla E, Brotis A, Korais C, Saratziotis A, Lachanas V, Skoulakis C
Department of ENT, University Hospital of Larissa, Larissa, Greece.
Department of Neurosurgery, University Hospital of Larissa, Larissa, Greece.
J Laryngol Otol. 2022 Nov;136(11):1014-1022. doi: 10.1017/S0022215121004436. Epub 2022 Jan 11.
To compare the efficacy and safety characteristics of endoscopic and microscopic stapes surgery based on current evidence.
A systematic literature search was conducted of three medical databases, focusing on randomised, controlled studies or observational studies. Data related to the efficacy and safety of each technique were extracted. Outcome data were summarised using the pooled mean differences or pooled odds ratios, along with their 95 per cent confidence intervals.
Thirteen studies were included in the meta-analysis. Success rate was evaluated by estimating air-bone gap improvement; this revealed comparable outcomes for the two techniques (mean difference = -0.20; 95 per cent confidence interval = -0.53, 0.14). No statistically significant difference was detected concerning post-operative complications, except for dysgeusia (odds ratio = -1.12; 95 per cent confidence interval = -1.97, -0.28) and pain (odds ratio = -2.00; 95 per cent confidence interval = -2.97, -1.04), which favoured the endoscopic approach.
Though both techniques result in commensurate outcomes concerning success rate, post-operative pain and dysgeusia favour the endoscopic approach. Further high-quality studies are needed to adequately compare the two methods.
基于现有证据比较内镜下和显微镜下镫骨手术的疗效和安全性特征。
对三个医学数据库进行系统文献检索,重点关注随机对照研究或观察性研究。提取与每种技术的疗效和安全性相关的数据。使用合并平均差或合并比值比及其95%置信区间对结果数据进行汇总。
荟萃分析纳入了13项研究。通过评估气骨导差改善情况来评估成功率;结果显示两种技术的结果相当(平均差=-0.20;95%置信区间=-0.53,0.14)。除味觉障碍(比值比=-1.12;95%置信区间=-1.97,-0.28)和疼痛(比值比=-2.00;95%置信区间=-2.97,-1.04)外,术后并发症方面未检测到统计学上的显著差异,内镜手术在这两方面更具优势。
虽然两种技术在成功率方面结果相当,但术后疼痛和味觉障碍方面内镜手术更具优势。需要进一步开展高质量研究以充分比较这两种方法。