Department of Dermatology, En Chu Kong Hospital, New Taipei City, Taiwan.
Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
J Formos Med Assoc. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. Epub 2022 Jan 5.
Pityriasis rosea (PR) is a self-limited disease with exanthematous papulosquamous rashes mostly associated with reactivation of human herpesvirus (HHV)-6 or HHV-7. PR-like eruptions, which occur along with peripheral eosinophilia, interface dermatitis, and eosinophils on histopathology, may result from medications or vaccinations. Previously, PR-like eruptions had been noted following vaccination for influenza or other vaccines. During this pandemic, acute COVID-19 infection has been related to PR or PR-like eruptions in several cases. Various COVID-19 vaccines associated with PR-like eruptions were rarely reported. Herein, we report a case of cutaneous PR-like eruptions following COVID-19 mRNA-1273 vaccination.
玫瑰糠疹(PR)是一种自限性疾病,其皮疹为斑丘疹鳞屑性,主要与人类疱疹病毒(HHV)-6 或 HHV-7 的再激活有关。PR 样疹伴有外周血嗜酸性粒细胞增多、界面性皮炎和组织病理学上的嗜酸性粒细胞,可能由药物或疫苗引起。以前,流感或其他疫苗接种后曾出现 PR 样疹。在本次大流行期间,有几例急性 COVID-19 感染与 PR 或 PR 样疹有关。与 PR 样疹相关的各种 COVID-19 疫苗很少有报道。在此,我们报告一例 COVID-19 mRNA-1273 疫苗接种后出现皮肤 PR 样疹。