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玫瑰糠疹样疹与 COVID-19 mRNA-1273 疫苗接种的关系:病例报告及文献复习。

Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review.

机构信息

Department of Dermatology, En Chu Kong Hospital, New Taipei City, Taiwan.

Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

出版信息

J Formos Med Assoc. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. Epub 2022 Jan 5.

Abstract

Pityriasis rosea (PR) is a self-limited disease with exanthematous papulosquamous rashes mostly associated with reactivation of human herpesvirus (HHV)-6 or HHV-7. PR-like eruptions, which occur along with peripheral eosinophilia, interface dermatitis, and eosinophils on histopathology, may result from medications or vaccinations. Previously, PR-like eruptions had been noted following vaccination for influenza or other vaccines. During this pandemic, acute COVID-19 infection has been related to PR or PR-like eruptions in several cases. Various COVID-19 vaccines associated with PR-like eruptions were rarely reported. Herein, we report a case of cutaneous PR-like eruptions following COVID-19 mRNA-1273 vaccination.

摘要

玫瑰糠疹(PR)是一种自限性疾病,其皮疹为斑丘疹鳞屑性,主要与人类疱疹病毒(HHV)-6 或 HHV-7 的再激活有关。PR 样疹伴有外周血嗜酸性粒细胞增多、界面性皮炎和组织病理学上的嗜酸性粒细胞,可能由药物或疫苗引起。以前,流感或其他疫苗接种后曾出现 PR 样疹。在本次大流行期间,有几例急性 COVID-19 感染与 PR 或 PR 样疹有关。与 PR 样疹相关的各种 COVID-19 疫苗很少有报道。在此,我们报告一例 COVID-19 mRNA-1273 疫苗接种后出现皮肤 PR 样疹。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/166b/8731224/7d4816208900/gr1_lrg.jpg

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