动脉内皮衍生舒张因子（AEDRF）并不抑制乳头肌或门静脉的收缩。
Arterial endothelium-derived relaxing factor (AEDRF) does not suppress papillary muscle or portal vein contractions.
作者信息
Vedernikov Y P, Vihert A M, Leisner H
机构信息
All-Union Cardiology Research Centre, U.S.S.R. Academy of Medical Sciences, Moscow.
出版信息
Eur J Pharmacol. 1987 Oct 27;142(3):471-4. doi: 10.1016/0014-2999(87)90091-4.
10(-6) M EDRF released from perfused arterial donor segments in a superfusion bioassay system, either spontaneously or stimulated by acetylcholine, did not inhibit the contractility of electrically stimulated right ventricle papillary muscle of pig, rabbit and rat. EDRF also did not inhibit spontaneously contracting rat portal vein and thus relaxed precontracted arterial rings denuded of endothelium. The results suggest that EDRF released by arterial endothelial cells is a local modulator of arterial smooth muscle and is not important for extraarterial tissue regulation.
在超灌注生物测定系统中，从灌注的动脉供体节段自发释放或由乙酰胆碱刺激释放的10（-6）M内皮舒张因子（EDRF），并不抑制猪、兔和大鼠经电刺激的右心室乳头肌的收缩性。EDRF也不抑制大鼠门静脉的自发收缩，因此可使预先收缩的去内皮动脉环舒张。这些结果表明，动脉内皮细胞释放的EDRF是动脉平滑肌的一种局部调节剂，对动脉外组织的调节并不重要。
Zotero 插件