Heterogeneity of the response of venous smooth muscle to arterial endothelium-derived relaxing factor (EDRF) in respect of the role of nitric oxide.
作者信息
Vedernikov Y P, Gräser T, Tiedt N, Vikhert A M
机构信息
Department of Human Cardiovascular Pathology, All-Union Cardiology Research Centre, Academy of Medical Sciences, Moscow, U.S.S.R.
出版信息
Basic Res Cardiol. 1988 Mar-Apr;83(2):122-7. doi: 10.1007/BF01907265.
PMID:3260772
Abstract
In bioassay and organ bath experiments, the responses of different canine venous preparations to arterial and their own EDRF were studied. Vena jugularis, vena femoralis and vena mesenterica relaxed on both EDRFs released by acetylcholine. Vena saphena, venae cordis and vena portae did not show endothelium-dependent dilation, either under bioassay or in organ bath experiments. All the veins tested relaxed completely after sodium nitroprusside administration. The identity of EDRF and nitric oxide is not confirmed by this study.
摘要
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本文引用的文献
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Role of endothelium in responses of vascular smooth muscle.内皮细胞在血管平滑肌反应中的作用。
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The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine.内皮细胞在乙酰胆碱介导的动脉平滑肌舒张中所起的不可或缺的作用。
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Venous response to endothelial denudation.静脉对内皮剥脱的反应。
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Arterial endothelium-derived relaxing factor (AEDRF) does not suppress papillary muscle or portal vein contractions.动脉内皮衍生舒张因子（AEDRF）并不抑制乳头肌或门静脉的收缩。
Eur J Pharmacol. 1987 Oct 27;142(3):471-4. doi: 10.1016/0014-2999(87)90091-4.
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Endothelium-derived relaxing factor is a selective relaxant of vascular smooth muscle.内皮源性舒张因子是血管平滑肌的一种选择性舒张剂。
J Pharmacol Exp Ther. 1987 Oct;243(1):55-60.
6
Is there an abluminal release of endothelium-derived relaxing factor (EDRF)?是否存在内皮源性舒张因子（EDRF）的管腔外释放？
Basic Res Cardiol. 1987 Mar-Apr;82(2):172-7. doi: 10.1007/BF01907064.
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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor.一氧化氮的释放构成了内皮源性舒张因子的生物活性。
Nature. 1987;327(6122):524-6. doi: 10.1038/327524a0.
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[Endothelial relaxation factor as a local modulator of arterial function. The possibility of stabilization].[内皮舒张因子作为动脉功能的局部调节因子。稳定的可能性]
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