Comparison of efficiency of complements from various species for T-cell depletion from Cercopithecus aethiops bone marrow with Campath-1 MoAb in vitro.
作者信息
Phan D T, Gidáli J, Fehér I, Harsányi V, Petrányi G G, Hollán S R
机构信息
National Institute of Haematology and Blood Transfusion, Budapest, Hungary.
出版信息
Haematologia (Budap). 1987;20(4):203-13.
PMID:3501389
Abstract
Mature T-cells were removed from Cercopithecus aethiops monkey bone marrow with Campath-1 MoAb plus complement from various species (man, rabbit and monkey). The T-cell depletion was more effective and stable with rabbit or human complement than with autologous (monkey) complement. The most complete and effective lytic function to T-cells was found in the case of rabbit complement. Rabbit complement can be used successfully to deplete bone marrow T-cells of C. aethiops with Campath-1 in vitro.
摘要
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