Department of General Surgery, Faculty of Medicine, Cairo University Hospitals Manial, Cairo, 11555, Egypt.
Obes Surg. 2022 Mar;32(3):779-785. doi: 10.1007/s11695-021-05874-0. Epub 2022 Jan 11.
Roux-en-Y gastric bypass (RYGB) is one of the most effective bariatric procedures. The study aimed to explore the value of lengthening the biliopancreatic limb (BPL) in RYGB compared to the outcome of one-anastomosis gastric bypass (OAGB).
This prospective study included morbidly obese patients divided into two groups. The RYGB group (n = 36) was subjected to long biliary limb Roux-en-Y gastric bypass (LPRYGB), and the OAGB Group (n = 36) had one anastomosis gastric bypass. During follow-up, weight, BMI, percentage of excess body weight loss (%EBWL), resolution of obesity-related comorbidities, and quality of life (QoL) were evaluated.
There was no significant difference in weight and BMI after 3 and 6 months. At 12-month follow-up, weight loss was significantly higher in the OAGB group. After 12 months, the two groups showed significant improvement of comorbid conditions without significant difference between the two groups. The Qol was significantly higher in the LPRYGB group 3, 6, and 12 months after surgery compared to the OAGB group.
Extending the BPL length in RYGB to 150 cm is as effective as OAGB in remission of comorbidities, including diabetes. It was also equally effective in weight reduction in the short term. OAGB was more efficient in weight reduction and a significantly faster operation. LPRYGB showed a better QoL of life 1 year after surgery.
Roux-en-Y 胃旁路术(RYGB)是最有效的减肥手术之一。本研究旨在探讨与单吻合口胃旁路术(OAGB)相比,延长胆胰支(BPL)在 RYGB 中的价值。
这项前瞻性研究纳入了肥胖症患者,分为两组。RYGB 组(n=36)接受长胆胰支 Roux-en-Y 胃旁路术(LPRYGB),OAGB 组(n=36)接受单吻合口胃旁路术。在随访期间,评估体重、BMI、超重体重减轻百分比(%EBWL)、肥胖相关合并症的缓解情况以及生活质量(QoL)。
术后 3 个月和 6 个月时体重和 BMI 无显著差异。在 12 个月的随访中,OAGB 组的体重减轻更为显著。在 12 个月时,两组的合并症均有明显改善,但两组之间无显著差异。与 OAGB 组相比,LPRYGB 组在术后 3、6 和 12 个月时的 QoL 显著提高。
在 RYGB 中延长 BPL 至 150cm 与 OAGB 一样有效,可以缓解包括糖尿病在内的合并症。在短期内,它在减轻体重方面也同样有效。OAGB 在减轻体重方面更为有效,且手术速度更快。LPRYGB 在术后 1 年时显示出更好的生活质量。