R&D Center for Membrane Technology and Department of Chemical Engineering, Chung Yuan Christian University, Taoyuan 320, Taiwan R.O.C.
Department of Chemical and Materials Engineering, National Central University, Taipei 32001, Taiwan R.O.C.
ACS Appl Bio Mater. 2022 Jan 17;5(1):225-234. doi: 10.1021/acsabm.1c01053. Epub 2021 Dec 25.
Air plasma and spray technology are common methods for surface modification. In this study, air plasma is used to generate hydroxyl groups on various material surfaces. Then random copolymers of styrene and ethylene glycol methacrylate (PS--PEGMA) are spray-coated to achieve coating densities ranging between 0.1 and 0.6 mg/cm. PS--PEGMA led to the best overall antifouling properties, while a coating density of 0.3 mg/cm was enough to significantly reduce biofouling. This surface modification technique enabled efficient modification of a wide range of materials and biofouling reduction by at least 75% on polymeric surfaces (polystyrene, polyvinylidene fluoride, poly(tetrafluoroethylene), polydimethylsiloxane), metallic surfaces (steel, titanium alloy), or ceramic surface (glass). Applied to the modification of well plate used for blood-typing, this antifouling modification permitted to greatly increase the signal sensitivity (×4).
空气等离子体和喷涂技术是常见的表面改性方法。在这项研究中，空气等离子体用于在各种材料表面生成羟基。然后喷涂随机共聚物苯乙烯和乙二醇甲基丙烯酸酯（PS-PEGMA），以实现 0.1 至 0.6mg/cm 之间的涂层密度。PS-PEGMA 导致了最佳的整体防污性能，而 0.3mg/cm 的涂层密度足以显著减少生物污垢。这种表面改性技术能够高效地改性多种材料，并将聚合物表面（聚苯乙烯、聚偏二氟乙烯、聚四氟乙烯、聚二甲基硅氧烷）、金属表面（钢、钛合金）或陶瓷表面（玻璃）上的生物污垢减少至少 75%。将其应用于用于血型鉴定的微孔板的改性，这种防污改性极大地提高了信号灵敏度（×4）。
