Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium.
Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
J Obstet Gynaecol. 2022 Jul;42(5):816-822. doi: 10.1080/01443615.2021.2003310. Epub 2022 Jan 11.
A caesarean section may lead to a defect of the myometrium at the site of the uterine scar. The association with abnormal uterine bleeding or impaired fertility has been demonstrated. Hysteroscopic remodelling reportedly reduces the symptoms. To review the available literature reporting on hysteroscopic treatment of these defects in symptomatic women with abnormal uterine bleeding or impaired fertility. A systematic search of PubMed and Cochrane databases has been performed until January 2021, including 27 articles. Hysteroscopic remodelling relieved symptoms of abnormal uterine bleeding in 60-100% and 25-100% of women with impaired fertility conceived within the follow up period. No major complications were reported. Hysteroscopic remodelling seems a treatment option in the management of symptomatic caesarean scar defects. Long-term follow-up and larger studies are needed to evaluate the effect on abnormal uterine bleeding as well as on reproductive outcomes.
剖宫产术可能导致子宫瘢痕部位的子宫肌层缺陷。已经证明其与异常子宫出血或生育能力受损有关。据报道,宫腔镜下子宫整形术可减轻症状。回顾分析报道宫腔镜治疗异常子宫出血或生育能力受损的有症状女性的这些缺陷的现有文献。系统检索了 PubMed 和 Cochrane 数据库,截至 2021 年 1 月,共纳入 27 篇文章。宫腔镜下子宫整形术可使异常子宫出血的症状缓解 60-100%,生育能力受损的女性在随访期间受孕率为 25-100%。未报告重大并发症。宫腔镜下子宫整形术似乎是治疗有症状剖宫产瘢痕缺陷的一种方法。需要长期随访和更大规模的研究来评估其对异常子宫出血以及生殖结局的影响。